公开(公告)号：US20070239990A1

公开(公告)日：2007-10-11

申请号：US11392028

申请日：2006-03-29

Applicant: Serge Fruhauf ,  David Tamagno ,  Andre Dostie ,  John Tran ,  Klaus Uehlecke ,  Sean Newton

Inventor： Serge Fruhauf ,  David Tamagno ,  Andre Dostie ,  John Tran ,  Klaus Uehlecke ,  Sean Newton

IPC: H04L9/00

CPC classification number: G06F21/32 ,  G06F21/80

Abstract: A USB mass storage device includes a memory, USB interface and USB controller. A biometric circuit provides biometric authentication and a secure microcontroller is operatively connected to the biometric circuit and the USB controller and operative in accordance as a trusted platform and having a command set to access security functions and trust authentication of a user using the biometric circuit.

Abstract translation: USB大容量存储设备包括存储器，USB接口和USB控制器。 生物识别电路提供生物特征认证，并且安全微控制器可操作地连接到生物测定电路和USB控制器，并且根据可信赖的平台进行操作，并且具有用于访问使用生物测定电路的用户的安全功能和信任认证的命令集。

公开(公告)号：US5728581A

公开(公告)日：1998-03-17

申请号：US482259

申请日：1995-06-07

Applicant: Richard Merrill Schwartz ,  Sean Newton Tucker ,  Srikanth Ranga Chary ,  Suzanne Chang Kuo

Inventor： Richard Merrill Schwartz ,  Sean Newton Tucker ,  Srikanth Ranga Chary ,  Suzanne Chang Kuo

IPC: C12M3/00 ,  C12M3/06 ,  C12N5/0789 ,  C12N5/00 ,  C12M1/22 ,  C12N5/02

CPC classification number: C12M25/06 ,  C12M23/02 ,  C12M23/04 ,  C12M23/24 ,  C12M25/02 ,  C12M41/32 ,  C12N5/0647 ,  C12N2500/02 ,  C12N2500/90 ,  C12N2501/125 ,  C12N2501/22 ,  C12N2501/23

Abstract: The present invention provides methods and bioreactors for expanding stem cells in a population of cells substantially enriched in hematopoietic stem cells and substantially free of stromal cells. The method comprising the steps of inoculating the population of cells in an expansion container in a volume of suitable medium such that the cell density is at least about 5,000 cells/1 mL and at an initial oxygen concentration of less than 8%; adding an effective amount of at least one cytokine to cause stem cell expansion; culturing the cells under suitable conditions such that the cells condition the medium; increasing the oxygen concentration to about 20%; exchanging the medium at a rate which allows expansion of the stem cells; and culturing the cells under conditions such that the stem cells are expanded. The present invention also provides a bioreactor constructed to accomodate the operational requirements for stroma-free stem cell expansion.

Abstract translation: 本发明提供用于在基本上富含造血干细胞并基本上不含基质细胞的细胞群中扩增干细胞的方法和生物反应器。 该方法包括以下步骤：将细胞群接种在一定体积的合适培养基中的膨胀容器中，使得细胞密度为至少约5,000个细胞/ mL，初始氧浓度小于8％; 加入有效量的至少一种细胞因子以引起干细胞扩张; 在合适的条件下培养细胞，使细胞调节培养基; 将氧浓度提高到约20％; 以允许干细胞扩增的速率交换培养基; 并在使干细胞扩大的条件下培养细胞。 本发明还提供了一种生物反应器，其被构造为适应无基质干细胞扩增的操作要求。

公开(公告)号：US09794247B2

公开(公告)日：2017-10-17

申请号：US11507679

申请日：2006-08-22

Applicant: Sean Newton ,  John Tran ,  David Tamagno

Inventor： Sean Newton ,  John Tran ,  David Tamagno

IPC: H04L29/06 ,  G03G21/18 ,  G06F21/31 ,  G03G15/08

CPC classification number: H04L63/0823 ,  G03G15/0863 ,  G03G21/1878 ,  G03G2215/0697 ,  G03G2221/1823 ,  G06F21/31 ,  G06F2221/2129 ,  H04L63/06

Abstract: An electronic component includes a processor and a memory. The electronic component has a secure platform capable of storing at least one dual key pair and a corresponding digital signature. There is also a system including a host machine and an electronic component capable of being operated by the host machine. The electronic component has a processor, a memory, and a secure platform capable of storing at least one dual key pair and a corresponding digital signature. Another aspect describes a method, which includes reading a public key from an electronic component by a host machine, verifying the public key against a stored key in the host machine, digitally signing data using a private key from the electronic component, verifying the signed data against the stored key, and using the electronic component by the host machine only if the signed data and the public key are verified.

公开(公告)号：US20080052518A1

公开(公告)日：2008-02-28

申请号：US11507679

申请日：2006-08-22

Applicant: Sean Newton ,  John Tran ,  David Tamagno

Inventor： Sean Newton ,  John Tran ,  David Tamagno

IPC: H04L9/00

CPC classification number: H04L63/0823 ,  G03G15/0863 ,  G03G21/1878 ,  G03G2215/0697 ,  G03G2221/1823 ,  G06F21/31 ,  G06F2221/2129 ,  H04L63/06

Abstract: An electronic component includes a processor and a memory. The electronic component has a secure platform capable of storing at least one dual key pair and a corresponding digital signature. There is also a system including a host machine and an electronic component capable of being operated by the host machine. The electronic component has a processor, a memory, and a secure platform capable of storing at least one dual key pair and a corresponding digital signature. Another aspect describes a method, which includes reading a public key from an electronic component by a host machine, verifying the public key against a stored key in the host machine, digitally signing data using a private key from the electronic component, verifying the signed data against the stored key, and using the electronic component by the host machine only if the signed data and the public key are verified.

Abstract translation: 电子部件包括处理器和存储器。 电子部件具有能够存储至少一个双重密钥对和对应的数字签名的安全平台。 还有一种包括主机和能够由主机操作的电子部件的系统。 电子部件具有处理器，存储器和能够存储至少一个双重密钥对和对应的数字签名的安全平台。 另一方面描述了一种方法，其包括由主机从电子组件读取公共密钥，根据主机中存储的密钥验证公钥，使用来自电子组件的专用密钥对数据进行数字签名，验证签名数据 仅当签名数据和公钥被验证时，才能使用主机的电子部件。