公开(公告)号：US07692059B2

公开(公告)日：2010-04-06

申请号：US11726100

申请日：2007-03-20

Applicant: Ethan Bier ,  Annabel Guichard ,  Shaila Srinivasan

Inventor： Ethan Bier ,  Annabel Guichard ,  Shaila Srinivasan

IPC: C12P21/00 ,  A01K67/033

CPC classification number: A01K67/0339 ,  A01K67/033 ,  A01K2217/05 ,  A01K2227/706 ,  A01K2267/03 ,  C07K14/34 ,  C12N15/8509

Abstract: Methods for generating and using novel overexpression activity alleles of a gene in any organism, especially Drosophilia, are provided. Such alleles may be utilized in screening assays, and used to generate dominant-negative forms of bacterial toxins.

Abstract translation: 提供了在任何生物体中产生和使用基因的新的过表达活性等位基因的方法，特别是果蝇。 这样的等位基因可用于筛选测定，并用于产生显性负性形式的细菌毒素。

公开(公告)号：US20070186291A1

公开(公告)日：2007-08-09

申请号：US11726100

申请日：2007-03-20

Applicant: Ethan Bier ,  Annabel Guichard ,  Shaila Srinivasan

Inventor： Ethan Bier ,  Annabel Guichard ,  Shaila Srinivasan

IPC: A01K67/033

CPC classification number: A01K67/0339 ,  A01K67/033 ,  A01K2217/05 ,  A01K2227/706 ,  A01K2267/03 ,  C07K14/34 ,  C12N15/8509

Abstract: Methods for generating and using novel overexpression activity alleles of a gene in any organism, especially Drosophilia, are provided. Such alleles may be utilized in screening assays, and used to generate dominant-negative forms of bacterial toxins.

公开(公告)号：US07193126B2

公开(公告)日：2007-03-20

申请号：US10263367

申请日：2002-10-01

Applicant: Ethan Bier ,  Annabel Guichard ,  Shaila Srinivasan

Inventor： Ethan Bier ,  Annabel Guichard ,  Shaila Srinivasan

IPC: A01K67/033

CPC classification number: A01K67/0339 ,  A01K67/033 ,  A01K2217/05 ,  A01K2227/706 ,  A01K2267/03 ,  C07K14/34 ,  C12N15/8509

Abstract: Methods for generating and using novel overexpression activity alleles of a gene in any organism, especially Drosophilia, are provided. Such alleles may be utilized in screening assays, and used to generate dominant-negative forms of bacterial toxins.

Abstract translation: 提供了在任何生物体中产生和使用基因的新的过表达活性等位基因的方法，特别是果蝇。 这样的等位基因可用于筛选测定，并用于产生显性负性形式的细菌毒素。