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公开(公告)号:US09765341B2
公开(公告)日:2017-09-19
申请号:US13882753
申请日:2011-11-04
申请人: Ido Bachelet , Shawn Douglas , George Church
发明人: Ido Bachelet , Shawn Douglas , George Church
IPC分类号: C12N15/115 , C12Q1/68 , C12N15/11 , A61K48/00 , C12N15/87
CPC分类号: C12N15/115 , A61K48/0025 , A61K48/0091 , C12N15/10 , C12N15/111 , C12N15/87 , C12N2310/16 , C12N2310/3519 , C12N2310/532 , C12N2320/32 , C12Q1/68 , C12Q2525/205
摘要: Provided herein are DNA origami devices useful in the targeted delivery of biologically active entities to specific cell populations.
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公开(公告)号:US08403128B2
公开(公告)日:2013-03-26
申请号:US13085960
申请日:2011-04-13
IPC分类号: B65G33/32
CPC分类号: B65G33/14 , B65G33/32 , Y10T29/49947
摘要: A screw conveyor to move media includes a first feed screw having a first end portion, a second feed screw having a second end portion, and a support hanger assembly to support the first feed screw and the second feed screw. The support hanger assembly includes a hanger bracket having a vertical support member and an inner hub secured to and extending perpendicularly from the vertical support member, a shaft portion disposed within the inner hub, an inner sleeve configured to be disposed between the shaft portion and the inner hub, at least one outer hub coupled to the shaft portion, and an outer sleeve configured to be disposed between the inner hub and the at least one outer hub. The first feed screw and the second feed screw are coupled to the at least one outer hub. The inner sleeve and/or the outer sleeve may be fabricated from low coefficient of friction material.
摘要翻译: 用于移动介质的螺旋输送机包括具有第一端部的第一进料螺杆,具有第二端部的第二进料螺杆和用于支撑第一进料螺杆和第二进料螺杆的支撑悬挂组件。 所述支撑衣架组件包括具有垂直支撑构件和固定到所述垂直支撑构件垂直方向并从所述垂直支撑构件垂直延伸的内轮毂的吊架支架;设置在所述内轮毂内的轴部,配置成设置在所述轴部和 内毂,联接到轴部的至少一个外毂,以及被配置为设置在内毂和至少一个外毂之间的外套。 第一进给螺杆和第二进给螺杆联接到至少一个外部毂。 内套筒和/或外套筒可以由低摩擦系数材料制成。
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公开(公告)号:US20120261236A1
公开(公告)日:2012-10-18
申请号:US13085960
申请日:2011-04-13
CPC分类号: B65G33/14 , B65G33/32 , Y10T29/49947
摘要: A screw conveyor to move media includes a first feed screw having a first end portion, a second feed screw having a second end portion, and a support hanger assembly to support the first feed screw and the second feed screw. The support hanger assembly includes a hanger bracket having a vertical support member and an inner hub secured to and extending perpendicularly from the vertical support member, a shaft portion disposed within the inner hub, an inner sleeve configured to be disposed between the shaft portion and the inner hub, at least one outer hub coupled to the shaft portion, and an outer sleeve configured to be disposed between the inner hub and the at least one outer hub. The first feed screw and the second feed screw are coupled to the at least one outer hub. The inner sleeve and/or the outer sleeve may be fabricated from low coefficient of friction material.
摘要翻译: 用于移动介质的螺旋输送机包括具有第一端部的第一进料螺杆,具有第二端部的第二进料螺杆和用于支撑第一进料螺杆和第二进料螺杆的支撑悬挂组件。 所述支撑衣架组件包括具有垂直支撑构件和固定到所述垂直支撑构件垂直方向并从所述垂直支撑构件垂直延伸的内轮毂的吊架支架;设置在所述内轮毂内的轴部,配置成设置在所述轴部和 内毂,联接到轴部的至少一个外毂,以及被配置为设置在内毂和至少一个外毂之间的外套。 第一进给螺杆和第二进给螺杆联接到至少一个外部毂。 内套筒和/或外套筒可以由低摩擦系数材料制成。
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公开(公告)号:US20130224859A1
公开(公告)日:2013-08-29
申请号:US13882753
申请日:2011-11-04
申请人: Ido Bachelet , Shawn Douglas , George Church
发明人: Ido Bachelet , Shawn Douglas , George Church
IPC分类号: C12N15/115
CPC分类号: C12N15/115 , A61K48/0025 , A61K48/0091 , C12N15/10 , C12N15/111 , C12N15/87 , C12N2310/16 , C12N2310/3519 , C12N2310/532 , C12N2320/32 , C12Q1/68 , C12Q2525/205
摘要: Provided herein are DNA origami devices useful in the targeted delivery of biologically active entities to specific cell populations.
摘要翻译: 本文提供了可用于向特定细胞群体靶向递送生物活性实体的DNA折纸装置。
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公开(公告)号:US06253601B1
公开(公告)日:2001-07-03
申请号:US09221625
申请日:1998-12-28
IPC分类号: G01M1500
CPC分类号: F01M11/10 , F01M2011/14 , F01M2011/1466 , F01M2011/1473 , F01M2011/1493
摘要: A system and method for indicating when the oil of an engine needs to be changed. The system includes measuring engine parameters such as engine temperature, fueling rate, engine speed, and engine load. At timed intervals, soot generation, viscosity increase, and total base number (TBN) depletion are estimated through a calculation for that time interval. The estimated values from the calculations are accumulated in separate loops. Once the accumulation of soot generation, oil viscosity increase, or TBN depletion reaches a predetermined magnitude for that respective oil property, then an indication or signal is provided to indicate to the engine operator that the oil needs changing. The system is supplemented with real time sensors such as an oil level sensor, a soot sensor, and a viscosity sensor which provide a back up for the calculation of estimates and also prevent catastrophic engine conditions from not being detected through electronic calculation of estimates. The system and method also can correct for the accumulation of oil consumption caused by evaporation of oil or leakage of oil. The algorithms used in the calculations can account for oil quality and fuel sulfur as well as the configuration of the engine, to allow the engine to be used in different geographic locations.
摘要翻译: 一种用于指示何时需要改变发动机油的系统和方法。 该系统包括测量发动机参数,如发动机温度,加油速率,发动机转速和发动机负荷。 按照时间间隔,通过计算该时间间隔估计烟炱产生,粘度增加和总碱值(TBN)耗尽。 来自计算的估计值累积在单独的循环中。 一旦烟灰产生的累积,油粘度增加或TBN耗尽达到相应油性质的预定量级,则提供指示或信号以向发动机操作者指示油需要改变。 该系统补充有实时传感器,例如油位传感器,烟尘传感器和粘度传感器,其提供用于估计的计算的备份,并且还通过电子计算估计来防止未检测到灾难性的发动机状况。 该系统和方法也可以纠正油蒸发或油渗漏引起的油耗累积。 计算中使用的算法可以解释油质和燃料硫以及发动机的配置,以允许发动机在不同的地理位置使用。
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