公开(公告)号：US20190177304A1

公开(公告)日：2019-06-13

申请号：US15834728

申请日：2017-12-07

申请人： Harry Ralph Howard ,  Dennis Michael Godek ,  Shawn-Michael Rodriguez

发明人： Harry Ralph Howard ,  Dennis Michael Godek ,  Shawn-Michael Rodriguez

IPC分类号： C07D405/04 ,  C07D413/04 ,  C07D417/04 ,  C07D409/04 ,  A61P33/02

CPC分类号： C07D405/04 ,  A61P33/02 ,  C07D409/04 ,  C07D413/04 ,  C07D417/04

摘要： The invention is directed to a compound of formula I, a pharmaceutically acceptable salt thereof, a pharmaceutical composition containing a compound of formula I, and a method of treatment of a disorder or condition in a mammal, including a human, selected from the group consisting of Human African Trypanosomiasis (HAT), Chagas disease, Leishmaniasis, toxoplasmosis and malaria.

公开(公告)号：US10351552B2

公开(公告)日：2019-07-16

申请号：US15834728

申请日：2017-12-07

申请人： Harry Ralph Howard ,  Dennis Michael Godek ,  Shawn-Michael Rodriguez

发明人： Harry Ralph Howard ,  Dennis Michael Godek ,  Shawn-Michael Rodriguez

IPC分类号： A61P33/02 ,  C07D405/04 ,  C07D409/04 ,  C07D413/04 ,  C07D417/04 ,  A61K31/343

摘要： The invention is directed to a compound of formula I, a pharmaceutically acceptable salt thereof, a pharmaceutical composition containing a compound of formula I, and a method of treatment of a disorder or condition in a mammal, including a human, selected from the group consisting of Human African Trypanosomiasis (HAT), Chagas disease, Leishmaniasis, toxoplasmosis and malaria.