公开(公告)号：US20080104722A1

公开(公告)日：2008-05-01

申请号：US11553125

申请日：2006-10-26

申请人： Junji Yodoi ,  Hiroshi Masutani ,  Shinichi Oka ,  Hajime Nakamura

发明人： Junji Yodoi ,  Hiroshi Masutani ,  Shinichi Oka ,  Hajime Nakamura

IPC分类号： A01K67/027

CPC分类号： C07K14/4703 ,  A01K67/0276 ,  A01K2217/075 ,  A01K2227/105 ,  A01K2267/0362 ,  C12N15/8509

摘要： The object of the invention is to provide animal model of disorder and method of screening an agent for preventing or treating Metabolic Syndrome by using the animal model, wherein said animal model is used as experimental material which is essential to detailed analysis of component and pathologic condition of Metabolic Syndrome and to development of the method for treating and the agent for preventing and treating the Metabolic Syndrome.The above object is achieved by the non-human mammal model of disorders, whose TBP-2 gene is functionally deficient on chromosome, wherein the disorders are caused by impaired fatty acid utilization, and a method of screening an agent for preventing or treating Metabolic syndrome comprising; administering a test article to the non-human mammal whose TBP-2 gene is functionally deficient on chromosome.

摘要翻译： 本发明的目的是提供动物模型的病症和筛选用于预防或治疗代谢综合征的药物的动物模型，其中所述动物模型被用作实验材料，其对于组分和病理状况的详细分析是必需的 的代谢综合征，并开发治疗方法和代谢综合征的预防和治疗药物。 上述目的是通过非人哺乳动物模型来实现的，其中TBP-2基因在染色体上功能缺陷，其中疾病是由脂肪酸利用受损引起的，以及筛选用于预防或治疗代谢综合征 包括; 对TBP-2基因在染色体上功能缺陷的非人哺乳动物施用测试物品。

公开(公告)号：US06765646B2

公开(公告)日：2004-07-20

申请号：US10233065

申请日：2002-08-30

申请人： Shinichi Oka ,  Satofumi Matsuyama ,  Makoto Kikuta ,  Hideharu Shiota

发明人： Shinichi Oka ,  Satofumi Matsuyama ,  Makoto Kikuta ,  Hideharu Shiota

IPC分类号： G03B2700

CPC分类号： G03D15/005

摘要： A print-order receiving apparatus is capable of receiving a customer's order for photographic prints through a recording medium electronically recording image data therein. The apparatus includes a box-like apparatus body, a slot formed in the apparatus body for attaching the recording medium and a reading driver unit for reading the image date from the recording medium as attached in the slot. The slot defines an aperture plane with its peripheral edges, the aperture plane being upwardly inclined.

摘要翻译： 打印订单接收装置能够通过其中的电子记录图像数据的记录介质来接收客户的照片订单。 该装置包括盒状装置主体，形成在装置主体中的用于安装记录介质的槽和用于从安装在槽中的记录介质读取图像日期的读取驱动单元。 狭槽限定了具有其外围边缘的孔平面，孔平面向上倾斜。

公开(公告)号：US20080182812A1

公开(公告)日：2008-07-31

申请号：US12026718

申请日：2008-02-06

申请人： Junji Yodoi ,  Hiroshi Masutani ,  Shinichi Oka ,  Hajime Nakamura

发明人： Junji Yodoi ,  Hiroshi Masutani ,  Shinichi Oka ,  Hajime Nakamura

IPC分类号： A61K31/711

CPC分类号： C07K14/4703 ,  A01K67/0276 ,  A01K2217/075 ,  A01K2227/105 ,  A01K2267/0362 ,  C12N15/8509

摘要： The object of the invention is to provide animal model of disorder and method of screening an agent for preventing or treating Metabolic Syndrome by using the animal model, wherein said animal model is used as experimental material which is essential to detailed analysis of component and pathologic condition of Metabolic Syndrome and to development of the method for treating and the agent for preventing and treating the Metabolic Syndrome.The above object is achieved by the non-human mammal model of disorders, whose TBP-2 gene is functionally deficient on chromosome, wherein the disorders are caused by impaired fatty acid utilization, and a method of screening an agent for preventing or treating Metabolic syndrome comprising; administering a test article to the non-human mammal whose TBP-2 gene is functionally deficient on chromosome.

公开(公告)号：US5533351A

公开(公告)日：1996-07-09

申请号：US256611

申请日：1994-09-23

申请人： Kenji Miyata ,  Hideki Tsujii ,  Shinichi Oka ,  Masaaki Takegami ,  Takeo Ueno ,  Tetsuya Suda

发明人： Kenji Miyata ,  Hideki Tsujii ,  Shinichi Oka ,  Masaaki Takegami ,  Takeo Ueno ,  Tetsuya Suda

IPC分类号： F25B1/00 ,  F25B13/00 ,  F25B43/00 ,  F25B41/00

CPC分类号： F25B43/006 ,  F25B13/00 ,  F25B2400/16

摘要： A reversibly operatable refrigerant circulating circuit (1) is formed in such a manner that a compressor (21), an outdoor heat exchanger (23), a motor-operated expansion valve (25) through which refrigerant flows in both directions and an indoor heat exchanger (31) are connected in this order. Between the motor-operated expansion valve (25) and the indoor heat exchanger (31), there is provided a refrigerant regulator (4) for regulating a circulation amount of refrigerant in a cooling operation cycle and storing liquefied refrigerant in a heating operation cycle. The refrigerant regulator (4) has a first flow pipe (42) to which the outdoor heat exchanger (23) is connected and a second flow pipe (43) which has plural refrigerant holes (45, 45 . . . ) and to which the indoor heat exchanger (31) is connected. Further, there is provided a widening control part (73) for controlling to widen an opening of the motor-operated expansion valve (25) when a pressure HP of high-pressure refrigerant in the refrigerant circulating circuit (1) reaches to a set value. Thus, an accumulator is dispensed with, an allowance range of a charge amount of refrigerant is widened and a rising of the pressure of high-pressure refrigerant is prevented.

摘要翻译： PCT No.PCT / JP93 / 01693 Sec。 371日期1994年9月23日 102（e）1994年9月23日PCT 1993年11月17日PCT公布。 第WO94 / 12834号公报 日期：1994年6月9日。可逆操作的制冷剂循环回路（1）形成为：制冷剂流过的压缩机（21），室外热交换器（23），电动膨胀阀（25） 并且室内热交换器31以这种顺序连接。 在电动膨胀阀（25）和室内热交换器（31）之间，设有制冷剂调节器（4），用于调节制冷运转循环中的制冷剂循环量，并在制热运转循环中储存液化制冷剂。 制冷剂调节器（4）具有与室外热交换器（23）连接的第一流量管（42）和具有多个制冷剂孔（45,45 ...）的第二流量管（43） 室内热交换器31连接。 此外，在制冷剂循环回路（1）中的高压制冷剂的压力HP达到设定值时，设置有用于控制电动膨胀阀（25）的开度变宽的加宽控制部（73） 。 因此，省略了蓄能器，制冷剂的充电量的允许范围变宽，并且防止了高压制冷剂的压力上升。