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公开(公告)号:US06710171B1
公开(公告)日:2004-03-23
申请号:US09380287
申请日:1999-11-16
IPC分类号: C07H2104
CPC分类号: C07K14/4703 , A01K2217/05 , A01K2217/075 , A61K38/00 , C07K14/705 , C07K14/82 , C07K2319/00
摘要: The present invention provides novel physiologically active protein molecules originating in mammals, which are specifically expressed in arteriosclerosis and/or coronary restenosis, and are predicted to relate closely to the onset and progress of these diseases; DNAs encoding the protein molecules; antibodies reactive with the molecules; and pharmaceutical compositions comprising the above protein molecule or the antibody. The protein molecules, DNAs, and antibodies are useful for treating and preventing arteriosclerosis.
摘要翻译: 本发明提供了起源于哺乳动物的新型生理活性蛋白质分子,其在动脉硬化和/或冠状动脉再狭窄中特异性表达,并被预测与这些疾病的发病和进展密切相关; 编码蛋白质分子的DNA; 与分子反应的抗体; 和包含上述蛋白质分子或抗体的药物组合物。 蛋白质分子,DNAs和抗体可用于治疗和预防动脉硬化。