Blood purification using plural ultrafiltration stages
    2.
    发明授权
    Blood purification using plural ultrafiltration stages 失效
    使用多个超滤阶段进行血液净化

    公开(公告)号:US4350594A

    公开(公告)日:1982-09-21

    申请号:US252245

    申请日:1981-04-08

    摘要: The invention provides a blood treatment apparatus realizing double-step-membrane filtration, namely separation of blood into plasma and a corpuscular fraction and separation of high-molecular-weight substances (e.g. gamma-globulin) in the plasma from low-molecular-weight substances (e.g. albumin). A method of treating blood is also provided.The apparatus and method are effective e.g. in the treatment of blood of patients with peripheral circulatory insufficiency due to arteriosclerosis and of patients with rheumatoid arthritis, which is an autoimmune disease.

    摘要翻译: 本发明提供一种实现双步膜过滤的血液处理装置,即将血液分离成血浆和红细胞级分,并从低分子量物质中分离血浆中的高分子量物质(如γ-球蛋白) (如白蛋白)。 还提供了一种治疗血液的方法。 该装置和方法是有效的。 在治疗由于动脉硬化引起的外周循环功能不全的患者和作为自身免疫性疾病的类风湿性关节炎患者的血液中。

    Oral preparations comprising S-(3-hydroxypropyl)-L-cysteine
    3.
    发明授权
    Oral preparations comprising S-(3-hydroxypropyl)-L-cysteine 有权
    包含S-(3-羟丙基)-L-半胱氨酸的口服制剂

    公开(公告)号:US06441040B1

    公开(公告)日:2002-08-27

    申请号:US09176155

    申请日:1998-10-21

    IPC分类号: A61K31195

    摘要: A preparation for oral administration which comprises S-(3-hydroxypropyl)-L-cysteine and one or more excipients, where the excipients do not cause discoloration of S-(3-hydroxypropyl)-L-cysteine is disclosled. According to an embodiment of the invention, the excipient may comprise a starch and/or a cyclodextrin. Typical starches used in the invention include corn starch, potato starch, wheat starch, and rice starch. Typical cyclodextrins used in the invention include &agr;-cyclodextrin, &bgr;-cyclodextrin, and &ggr;-cyclodextrin. Other excipients, such as saccharides, sugar alcohols and cellulose are not present in amounts that cause discoloration of the HPCY.

    摘要翻译: 公开了一种口服给药的制剂,其包含S-(3-羟丙基)-L-半胱氨酸和一种或多种赋形剂,其中赋形剂不引起S-(3-羟丙基)-L-半胱氨酸的变色。 根据本发明的一个实施方案,赋形剂可以包含淀粉和/或环糊精。 用于本发明的典型淀粉包括玉米淀粉,马铃薯淀粉,小麦淀粉和米淀粉。 用于本发明的典型环糊精包括α-环糊精,β-环糊精和γ-环糊精。 其它赋形剂,例如糖,糖醇和纤维素不以导致HPCY变色的量存在。