公开(公告)号：US20090071068A1

公开(公告)日：2009-03-19

申请号：US12283484

申请日：2008-09-12

Applicant: John Cook ,  Silas P. Cook

Inventor： John Cook ,  Silas P. Cook

IPC: C10L10/06

CPC classification number: C10L10/06 ,  C10L5/00 ,  C10L5/44 ,  Y02E50/10 ,  Y02E50/30

Abstract: A composition and method for creosote control in firebox flues burning solid fuels combines hydrophobic metal additives with a fire accelerant. According to certain embodiments, the compositions may inhibit corrosion of metal flues in addition to creosote deposits. When the metal salts are added to an accelerant at effective concentrations, the combination delivers the metal catalyst to the lining of the exhaust system upon combustion. As such, the metals are conveniently and efficiently transported up the flue.

Abstract translation: 燃烧固体燃料的火炉烟道中的杂酚油控制的组合物和方法将疏水性金属添加剂与消防加速剂结合。 根据某些实施方案，除了杂酚油沉积物之外，组合物可以抑制金属烟道的腐蚀。 当金属盐以有效浓度加入到促进剂中时，该组合在燃烧时将金属催化剂递送到排气系统的衬里。 因此，金属方便有效地传送到烟道上。

公开(公告)号：US08067462B2

公开(公告)日：2011-11-29

申请号：US11793646

申请日：2005-12-20

Applicant: Samuel J. Danishefsky ,  Silas P. Cook

Inventor： Samuel J. Danishefsky ,  Silas P. Cook

IPC: A61K31/34 ,  C07D307/77

CPC classification number: C07D307/93

Abstract: A compound having the structure of the formula (genus of compound 1 excluding Tashironin or Debenzoyltashironin) and methods of the same.

Abstract translation: 具有下式结构的化合物（不包括Tashironin或Debenzoyltashironin的化合物1属）及其方法。

公开(公告)号：US20090105332A1

公开(公告)日：2009-04-23

申请号：US11793646

申请日：2005-12-20

Applicant: Samuel J. Danishefsky ,  Silas P. Cook

Inventor： Samuel J. Danishefsky ,  Silas P. Cook

IPC: A61K31/343 ,  C07D307/93 ,  C07C49/323 ,  A61K31/122

CPC classification number: C07D307/93

Abstract: A compound having the structure of the formula (genus of compound 1 excluding Tashironin or Debenzoyltashironin) wherein, R1 is H or Bz when no more than three of R8, R9, R10 and R11 are H, or R1 is Bn, (C1-C4) alkyl, or CF3; R2 is H, (C1-C4) alkyl, halide, OC(O)(C1-C4)alkyl, OC(O)Ph, or OCF3; R3 is p-toluene sulfonyloxy, methane sulfonyloxy, C(O)(C1-C4)alkyl, or OC(O)(C1-C4)alkyl, bond α is a single bond, and bond β is a double bond or R3 is O, bond α is a double bond and bond β is a single bond; R4 is H, I, Br, Cl, Si(CH3)3, (C1-C4)alkyl, or OCF3; R5 is OH, OSi(CH3)3, O(C1-C4) alkyl, or OCF3, and bond γ is a single bond, or R5 is O and bond γ is a double bond; R6 is H, (C1-C4) alkyl, or CF3; R7 is H, OH, (C1-C4)alkyl, CH2OBn, CH2O(C1-C4)alkyl, CH2OH, halide, CH2OCF3 or OCF3 and bond ε is a single bond, or R7 is CH2 and bond ε is a double bond; R8, R9, and R10 are each independently H, (C1-C4)alkyl, halide, OH, or OCF3; R11 is H, (C1-C4)alkyl, halide, OH, or OCF3 and bond δ is a single bond; R12 is H, (C1-C4)alkyl, O(C1-C4)alkyl, p-toluene sulfonyloxy or methane sulfonyloxy, halide, OH, OCF3, or R15R16Si, where R15 and R16 are each independently (C1-C4)alkyl, furanyl or Ph, and bond δ is a single bond; R11 together with R12 and the carbons to which each is attached to form an oxirane moiety form an ether group and bond δ is a single bond; or R11 and R12 are absent and bond δ is a double bond. Also disclosed are processes for preparation of the composition.

Abstract translation: 具有式（除Tashironin或Debenzoyltashironin之外的化合物1属）的化合物，其中当R8，R9，R10和R11不超过三个时，R 1为H或Bz为H，或R 1为Bn，（C 1 -C 4） ）烷基或CF 3; R 2是H，（C 1 -C 4）烷基，卤素，OC（O）（C 1 -C 4）烷基，OC（O）Ph或OCF 3; R3是对甲苯磺酰氧基，甲磺酰氧基，C（O）（C1-C4）烷基或OC（O）（C1-C4）烷基，键α是单键，键β是双键或R3是 O，键α是双键，键β是单键; R4是H，I，Br，Cl，Si（CH3）3，（C1-C4）烷基或OCF3; R5是OH，OSi（CH3）3，O（C1-C4）烷基或OCF3，键γ是单键，或R5是O，键γ是双键; R6是H，（C1-C4）烷基或CF3; R 7是H，OH，（C 1 -C 4）烷基，CH 2 OBn，CH 2 O（C 1 -C 4）烷基，CH 2 OH，卤素，CH 2 OCF 3或OCF 3，键ε是单键，或者R 7是CH 2，键ε是双键; R 8，R 9和R 10各自独立地为H，（C 1 -C 4）烷基，卤素，OH或OCF 3; R11是H，（C1-C4）烷基，卤素，OH或OCF3，键δ是单键; R 12是H，（C 1 -C 4）烷基，O（C 1 -C 4）烷基，对甲苯磺酰氧基或甲磺酰氧基，卤化物，OH，OCF 3或R 15 R 16 Si，其中R 15和R 16各自独立地为（C 1 -C 4）烷基， 呋喃基或Ph，键三角是单键; R 11与R 12和各自连接的碳形成环氧乙烷部分形成醚基团，键δ是单键; 或R 11和R 12不存在，键δ是双键。 还公开了组合物的制备方法。