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公开(公告)号:US20080181890A1
公开(公告)日:2008-07-31
申请号:US11929742
申请日:2007-10-30
申请人: Gregory Alan Lazar , Arthur J. Chirino , Wei Dang , John R. Desjarlais , Stephen Kokl Doberstein , Robert J. Hayes , Sher Bahadur Karki , Omid Vafa
发明人: Gregory Alan Lazar , Arthur J. Chirino , Wei Dang , John R. Desjarlais , Stephen Kokl Doberstein , Robert J. Hayes , Sher Bahadur Karki , Omid Vafa
IPC分类号: A61K39/395 , C07K16/00
CPC分类号: C07K16/00 , A61K2039/505 , C07K16/22 , C07K16/283 , C07K16/2863 , C07K16/2887 , C07K16/2893 , C07K16/2896 , C07K16/30 , C07K16/3015 , C07K16/32 , C07K2317/34 , C07K2317/52 , C07K2317/71 , C07K2317/72 , C07K2317/732 , C07K2317/734 , C07K2317/77 , C07K2317/92
摘要: The present invention relates to optimized Fc variants, methods for their generation, and antibodies and Fc fusions comprising optimized Fc variants.