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公开(公告)号：US20140057976A1
公开(公告)日：2014-02-27
申请号：US14008376
申请日：2012-03-26
IPC分类号： A61K31/343
CPC分类号： A61K47/22 , A61K9/0014 , A61K31/343 , A61K31/60 , A61K47/14 , A61K47/26 , A61K2300/00
摘要： Topical skin treatment formulation containing usnic acid or an usnate salt, dissolved in a solvent system comprising (i) dimethyl isosorbide; (ii) a C1 to C9 alkyl salicylate; and (iii) a glyceryl fatty acid ester. The solvent system may also comprise an alcohol, a polyoxyalkylene-based solvent, and/or a C1 to C4 alkyl glucose ester. The formulation may be used in the treatment of microbial conditions, in particular acne. The solvent system assists in the effective dissolution of the usnic acid or usnate and in targeting its delivery to relevant sites on the skin.
摘要翻译： 含有芥酸或盐酸盐的局部皮肤处理制剂，其溶解于包含（i）二甲基异山梨醇的溶剂体系中; （ii）C1至C9烷基水杨酸酯; 和（iii）甘油脂肪酸酯。 溶剂系统还可以包含醇，聚氧化烯基溶剂和/或C1至C4烷基葡萄糖酯。 该制剂可用于治疗微生物条件，特别是痤疮。 溶剂系统有助于有效溶解酸性酸或渗透液，并将其输送到皮肤上的相关部位。
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公开(公告)号：US20140107081A1
公开(公告)日：2014-04-17
申请号：US14008371
申请日：2012-03-26
CPC分类号： A61K47/22 , A61K9/0014 , A61K31/343 , A61K31/60 , A61K47/14 , A61K47/26 , A61K2300/00
摘要： Topical skin treatment formulation containing salicylic acid or a derivative thereof, dissolved in a solvent system comprising (i) dimethyl isosorbide; (ii) a C1 to C9 alkyl salicylate; and (iii) a glyceryl fatty acid ester. The solvent system may also comprise an alcohol, a polyoxyalkylene-based solvent, and/or a C1 to C4 alkyl glucose ester. The formulation may be used in the treatment of acne. The solvent system improves the targeted delivery of the salicylic acid or derivative to relevant sites on the skin.
摘要翻译： 含有水杨酸或其衍生物的局部皮肤处理制剂溶于溶剂体系中，该溶剂体系包含（i）二甲基异山梨醇酯; （ii）C1至C9烷基水杨酸酯; 和（iii）甘油脂肪酸酯。 溶剂系统还可以包含醇，聚氧化烯基溶剂和/或C1至C4烷基葡萄糖酯。 该制剂可用于治疗痤疮。 溶剂系统改善了水杨酸或衍生物在皮肤上相关部位的靶向递送。
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