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公开(公告)号：US20140057976A1
公开(公告)日：2014-02-27
申请号：US14008376
申请日：2012-03-26
IPC分类号： A61K31/343
CPC分类号： A61K47/22 , A61K9/0014 , A61K31/343 , A61K31/60 , A61K47/14 , A61K47/26 , A61K2300/00
摘要： Topical skin treatment formulation containing usnic acid or an usnate salt, dissolved in a solvent system comprising (i) dimethyl isosorbide; (ii) a C1 to C9 alkyl salicylate; and (iii) a glyceryl fatty acid ester. The solvent system may also comprise an alcohol, a polyoxyalkylene-based solvent, and/or a C1 to C4 alkyl glucose ester. The formulation may be used in the treatment of microbial conditions, in particular acne. The solvent system assists in the effective dissolution of the usnic acid or usnate and in targeting its delivery to relevant sites on the skin.
摘要翻译： 含有芥酸或盐酸盐的局部皮肤处理制剂，其溶解于包含（i）二甲基异山梨醇的溶剂体系中; （ii）C1至C9烷基水杨酸酯; 和（iii）甘油脂肪酸酯。 溶剂系统还可以包含醇，聚氧化烯基溶剂和/或C1至C4烷基葡萄糖酯。 该制剂可用于治疗微生物条件，特别是痤疮。 溶剂系统有助于有效溶解酸性酸或渗透液，并将其输送到皮肤上的相关部位。
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2.发明申请ANTIBACTERIAL OR ANTI-ACNE FORMULATIONS CONTAINING USNIC ACID OR AN USNATE AND A METAL SALT 审中-公开含有芥末酸或金属盐的抗生素或抗坏血酸配方公开(公告)号：US20130316016A1
公开(公告)日：2013-11-28
申请号：US13996427
申请日：2011-12-20
IPC分类号： A61K31/343 , A61K33/24 , A61K33/34
CPC分类号： A61K31/343 , A61K9/0014 , A61K9/06 , A61K9/12 , A61K33/24 , A61K33/245 , A61K33/34 , A61K2300/00
摘要： An antibacterial or anti-acne formulation suitable for topical or local application to human skin containing (a) either usnic acid or an usnate and (b) a metal salt selected from copper salts, bismuth salts, and mixtures thereof, wherein if the component (a) is an usnate, the components (a) and (b) are not the same compound.
摘要翻译： 一种抗皮肤或抗痤疮制剂，其适用于皮肤或局部施用于人体皮肤，所述皮肤含有（a）使用酸或丝氨酸和（b）选自铜盐，铋盐及其混合物的金属盐，其中如果组分（ a）是一个usnate，组分（a）和（b）不是相同的化合物。
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公开(公告)号：US20090030086A1
公开(公告)日：2009-01-29
申请号：US11909072
申请日：2006-03-23
IPC分类号： A61K31/122 , A61P31/04
CPC分类号： A61K8/347 , A61K8/355 , A61K8/38 , A61Q17/005 , A61Q19/00
摘要： A benzoquinone or hydroquinone for use in the topical treatment of a condition which is caused, exacerbated or transmitted by bacterial, in particular staphylococcal or propionibacterial, activity. The condition may be a skin or skin structure condition such as acne. The invention also provides the use of a benzo- or hydroquinone in the manufacture of a medicament for the treatment of such a condition.
摘要翻译： 用于局部治疗由细菌，特别是葡萄球菌或丙酸杆菌活性引起，加剧或传播的病症的苯醌或氢醌。 该病症可能是皮肤或皮肤结构状况，如痤疮。 本发明还提供苯并或氢醌在制备用于治疗这种病症的药物中的用途。
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公开(公告)号：US20080262097A1
公开(公告)日：2008-10-23
申请号：US11909066
申请日：2006-03-23
IPC分类号： A61K31/075 , A01N31/06 , A01P1/00 , A61P31/04
CPC分类号： A61K8/347 , A61K8/355 , A61K8/38 , A61Q17/005 , A61Q19/00
摘要： An antimicrobial formulation containing (a) a peroxide selected from the group consisting of diacyl peroxides, alkyl hydroperoxides and metal peroxides and (b) a benzoquinone or hydroquinone. The formulation may in particular be used against staphylococci or propionibacteria, more particularly to treat skin and skin structure conditions such as acne.
摘要翻译： 一种抗微生物制剂，其含有（a）选自二酰基过氧化物，烷基氢过氧化物和金属过氧化物的过氧化物和（b）苯醌或氢醌。 该制剂可以特别用于抵抗葡萄球菌或丙酸杆菌，更具体地说是用于治疗皮肤和皮肤结构条件如痤疮。
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