Biocompatible controlled release coatings for medical devices and related methods
    1.
    发明授权
    Biocompatible controlled release coatings for medical devices and related methods 有权
    用于医疗器械和相关方法的生物相容性控释涂层

    公开(公告)号:US08088404B2

    公开(公告)日:2012-01-03

    申请号:US11005463

    申请日:2004-12-06

    IPC分类号: A61F2/04 A61F2/00

    摘要: Biocompatible coatings for medical devices are disclosed. Specifically, polymer coatings designed to control the release of bioactive agents from medical devices in vivo are disclosed wherein the solubility parameters of polymers and drugs are closely matched to control elute rate profiles. The present application also discloses providing vascular stents with controlled release coatings and related methods for making these coatings.

    摘要翻译: 公开了用于医​​疗装置的生物相容性涂层。 具体地,公开了设计用于在体内控制生物活性剂从医疗装置释放的聚合物涂层,其中聚合物和药物的溶解度参数与控制洗脱速率曲线紧密匹配。 本申请还公开了提供具有控制释放涂层的血管支架和用于制备这些涂层的相关方法。