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    Accommodating intraocular lens
    5.
    发明授权
    Accommodating intraocular lens 有权
    容纳人工晶状体

    公开(公告)号：US08715345B2

    公开(公告)日：2014-05-06

    申请号：US13761024

    申请日：2013-02-06

    Applicant: California Institute of Technology ,  University of Southern California

    Inventor： Charles DeBoer ,  Yu-Chong Tai ,  Mark Humayun

    IPC: A61F2/16

    CPC classification number: A61F2/1613 ,  A61F2/1635 ,  A61F9/0017 ,  A61F2250/0003 ,  A61L27/48 ,  A61L2430/16 ,  C08L65/04

    Abstract: Systems, devices, and methods are presented for a prosthetic injectable intraocular lens. The lenses can be made from silicone, fluorosilicone, and phenyl substituted silicone and be semipermeable to air. One or more silicone elastomeric patches located outside the optical path on the anterior side but away from the equator can be accessed by surgical needles in order to fill or adjust optically clear fluid within the lens. The fluid can be adjusted in order to set a base dioptric power of the lens and otherwise adjust a lens after its initial insertion. The elastomeric patches are sized so that they self-seal after a needle is withdrawn. A straight or stepped slit in the patch can allow a blunt needle to more easily access the interior of the lens.

    Abstract translation: 系统，装置和方法用于假体可注射的眼内透镜。 透镜可以由硅酮，氟硅酮和苯基取代的硅氧烷制成，并且对透气半透膜。 可以通过外科手术针来访问位于前侧但远离赤道的光路外侧的一个或多个有机硅弹性体贴片，以便填充或调整透镜内的光学透明流体。 可以调节流体以便设置透镜的基础屈光度，并在其初始插入之后调整透镜。 弹性体贴片的尺寸使得它们在针被取出后自我密封。 贴片中的直的或阶梯的狭缝可以使钝针更容易地进入透镜的内部。

    RESIN COMPOSITION FOR SEALING ELECTRICAL ELECTRONIC COMPONENTS, METHOD OF PRODUCING ELECTRICAL ELECTRONIC COMPONENT, AND SEALED ELECTRICAL ELECTRONIC COMPONENT
    7.
    发明申请
    RESIN COMPOSITION FOR SEALING ELECTRICAL ELECTRONIC COMPONENTS, METHOD OF PRODUCING ELECTRICAL ELECTRONIC COMPONENT, AND SEALED ELECTRICAL ELECTRONIC COMPONENT 有权
    用于密封电子元件的树脂组合物，电子电子元件的制造方法和密封电子元件

    公开(公告)号：US20130331521A1

    公开(公告)日：2013-12-12

    申请号：US14000943

    申请日：2012-02-21

    Applicant: Daiki Funaoka ,  Kenji Shiga

    Inventor： Daiki Funaoka ,  Kenji Shiga

    IPC: C08L67/03 ,  C08L23/08 ,  C08L23/06 ,  C08L65/04 ,  C08L71/08

    CPC classification number: C08L67/03 ,  C08L23/02 ,  C08L23/06 ,  C08L23/08 ,  C08L23/0815 ,  C08L65/04 ,  C08L67/00 ,  C08L71/08 ,  C09K3/10 ,  C09K2200/0617 ,  C09K2200/0655 ,  C09K2200/0672 ,  H01L23/293 ,  H01L2924/0002 ,  C08L61/18 ,  C08L61/06 ,  H01L2924/00

    Abstract: It is provided that a resin composition for sealing electrical electronic components which is not susceptible to gelation even when stagnant under high temperature conditions, and which are excellent in initial bond strength to an aluminum material, and which exhibits superior durability under a cooling and heating cycle load and the like. It is also provided that a sealed electrical electronic component with the resin composition for sealing electrical electronic components. A resin composition for sealing electrical electronic components, containing a crystalline polyester-based elastomer (A), a phenol-modified xylene resin (B1) and/or a phenol resin (B2), and a polyolefin resin (C), and having a melt viscosity of 5 dPa·s or more and 3000 dPa·s or less when dried to a water content of 0.1% or less, heated to 220° C., subjected to a pressure of 1 MPa, and extruded through a die with a hole diameter of 1.0 mm and a thickness of 10 mm.

    Abstract translation: 本发明提供一种用于密封电子电子部件的树脂组合物，即使在高温条件下停滞时也不易凝胶化，并且与铝材料的初始结合强度优异，并且在冷却和加热循环下表现出优异的耐久性 负载等。 还提供了具有用于密封电子电子部件的树脂组合物的密封电子电子部件。 含有结晶性聚酯类弹性体（A），苯酚改性二甲苯树脂（B1）和/或酚醛树脂（B2）和聚烯烃树脂（C）的电子电子部件密封用树脂组合物，具有 当干燥至含水量为0.1％以下时的熔融粘度为5dPa·s以上且3000dPa·s以下，加热至220℃，进行1MPa的压力，并通过模具挤出 孔直径为1.0mm，厚度为10mm。

    ACCOMMODATING INTRAOCULAR LENS
    8.
    发明申请
    ACCOMMODATING INTRAOCULAR LENS 有权
    住院镜片

    公开(公告)号：US20130150960A1

    公开(公告)日：2013-06-13

    申请号：US13761024

    申请日：2013-02-06

    Applicant: California Institute of Technology ,  University of Southern California

    Inventor： Charles DeBoer ,  Yu-Chong Tai ,  Mark Humayun

    IPC: A61F2/16

    CPC classification number: A61F2/1613 ,  A61F2/1635 ,  A61F9/0017 ,  A61F2250/0003 ,  A61L27/48 ,  A61L2430/16 ,  C08L65/04

    Abstract: Systems, devices, and methods are presented for a prosthetic injectable intraocular lens. The lenses can be made from silicone, fluorosilicone, and phenyl substituted silicone and be semipermeable to air. One or more silicone elastomeric patches located outside the optical path on the anterior side but away from the equator can be accessed by surgical needles in order to fill or adjust optically clear fluid within the lens. The fluid can be adjusted in order to set a base dioptric power of the lens and otherwise adjust a lens after its initial insertion. The elastomeric patches are sized so that they self-seal after a needle is withdrawn. A straight or stepped slit in the patch can allow a blunt needle to more easily access the interior of the lens.

    Abstract translation: 系统，装置和方法用于假体可注射的眼内透镜。 透镜可以由硅酮，氟硅酮和苯基取代的硅氧烷制成，并且对透气半透膜。 可以通过外科手术针来访问位于前侧但远离赤道的光路外侧的一个或多个有机硅弹性体贴片，以便填充或调整透镜内的光学透明流体。 可以调节流体以便设置透镜的基础屈光度，并在其初始插入之后调整透镜。 弹性体贴片的尺寸使得它们在针被取出后自我密封。 贴片中的直的或阶梯的狭缝可以使钝针更容易地进入透镜的内部。

    Cell culture substrate and its production method
    9.
    发明授权
    Cell culture substrate and its production method 有权
    细胞培养基质及其制备方法

    公开(公告)号：US08383409B2

    公开(公告)日：2013-02-26

    申请号：US13020193

    申请日：2011-02-03

    Applicant: Shin Ohya ,  Takashi Inoue ,  Takatoki Yamamoto ,  Teruo Fujii ,  Yasuyuki Sakai ,  Masaki Nishikawa ,  Hitomi Sakai ,  Hirosuke Naruto

    Inventor： Shin Ohya ,  Takashi Inoue ,  Takatoki Yamamoto ,  Teruo Fujii ,  Yasuyuki Sakai ,  Masaki Nishikawa ,  Hitomi Sakai ,  Hirosuke Naruto

    IPC: C12N5/02

    CPC classification number: C12N5/0068 ,  C08G2261/3424 ,  C08L65/04 ,  C12N2533/30

    Abstract: The invention is directed to methods for the propagation or cultivation of cells including preparing a cell culture substrate, wherein the cell culture substrate includes a substrate and a layer formed by surface modification. The layer includes a polymer containing an amino group. The polymer is produced by reacting a polymer represented by formula (II): with a polymer having at least one amino group, —NH2, capable of forming a Schiff base in a monomer of formula (II), thereby forming a polymer layer constituting the layer formed by surface modification. “n” in Formula (II) is 0 or a positive integer, and m is a positive integer. n and m represent the degree of polymerization. Formula (II) is formed by chemical vapor deposition of formyl[2.2]paracyclophane. The methods further include providing cells in a medium; inoculating the cells onto the cell culture substrate; and culturing the cells, wherein the cells adhere to the cell culture substrate.

    Abstract translation: 本发明涉及细胞繁殖或培养方法，包括制备细胞培养基质，其中细胞培养基质包括基质和通过表面改性形成的层。 该层包括含有氨基的聚合物。 该聚合物通过使由式（II）表示的聚合物与具有至少一个氨基的聚合物-NH 2反应生成，该聚合物能够在式（II）的单体中形成席夫碱，从而形成构成 通过表面改性形成的层。 式（II）中的n为0或正整数，m为正整数。 n和m表示聚合度。 式（II）由甲酰基[2.2]对环磷酰胺的化学气相沉积形成。 所述方法还包括在培养基中提供细胞; 将细胞接种到细胞培养基底上; 并培养细胞，其中细胞粘附于细胞培养基质。

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