公开(公告)号：US08486996B2

公开(公告)日：2013-07-16

申请号：US11433511

申请日：2006-05-12

Applicant: Martin Eberle ,  Felix Bachmann ,  Alessandro Strebel ,  Subho Roy ,  Goutam Saha ,  Subir Kumar Sadhukhan ,  Rohit Saxena ,  Sudhir Srivastava

Inventor： Martin Eberle ,  Felix Bachmann ,  Alessandro Strebel ,  Subho Roy ,  Goutam Saha ,  Subir Kumar Sadhukhan ,  Rohit Saxena ,  Sudhir Srivastava

IPC: A61K31/34 ,  C07D307/87

CPC classification number: C07D213/85

Abstract: The invention relates to novel substituted 2-(phenyl-, pyridyl- or pyrimidyl-carbonyl)-furanes and -thiophenes and related phenoxy/phenylthio-acetophenones and corresponding heterocyclic compounds, processes for the preparation thereof, pharmaceutical compositions containing same, the use thereof optionally in combination with one or more other pharmaceutically active compounds for the therapy of neoplastic diseases and autoimmune diseases, and a method for the treatment of such a diseases.

Abstract translation: 本发明涉及新的取代的2-（苯基 - ，吡啶基或嘧啶基 - 羰基） - 呋喃和 - 噻吩和相关的苯氧基/苯硫基 - 苯乙酮及其相应的杂环化合物，其制备方法，含有它们的药物组合物，其用途 任选地与一种或多种用于治疗肿瘤性疾病和自身免疫疾病的其它药学活性化合物组合，以及治疗这种疾病的方法。