公开(公告)号：US06593360B1

公开(公告)日：2003-07-15

申请号：US09959204

申请日：2002-01-22

申请人： Gorjana Lazarevski ,  Sulejman Alihod{haeck over (z)}ić ,  Gabrijela Kobrehel ,  Stjepan Mutak

发明人： Gorjana Lazarevski ,  Sulejman Alihod{haeck over (z)}ić ,  Gabrijela Kobrehel ,  Stjepan Mutak

IPC分类号： C07H1708

CPC分类号： C07H17/08

摘要： The invention relates to novel 15-membered 8a- and 9a-lactams from the class of 6-O-methyl-erythromycin A of general formula (I) their pharmaceutically acceptable addition salts with inorganic or organic acids and their hydrates, to intermediates for their preparation, to a process for their preparation, to their pharmaceutically acceptable addition salts with inorganic or organic acids, to their hydrates, to a process for the preparation of pharmaceutical compositions as well as to a use of pharmaceutical compositions for the treatment of bacterial infections.

摘要翻译： 本发明涉及由通式（I）的6-O-甲基 - 红霉素A类别的与无机或有机酸及其水合物的药学上可接受的加成盐与其中间体的新型15-元8a-和9-内酰胺， 制备，其制备方法，其与无机或有机酸的药学上可接受的加成盐，其水合物，制备药物组合物的方法以及药物组合物用于治疗细菌感染的用途。