Recycling System for Manipulation of Intracellular NADH Availability
    2.
    发明申请
    Recycling System for Manipulation of Intracellular NADH Availability 审中-公开
    用于操作细胞内NADH可用性的回收系统

    公开(公告)号:US20100184195A1

    公开(公告)日:2010-07-22

    申请号:US12705170

    申请日:2010-02-12

    IPC分类号: C12N1/21

    CPC分类号: C12N9/0036 C12P1/00 C12P7/625

    摘要: The present invention describes a novel recombinant NADH recycling system that is used as a process for producing reduced compounds. In a specific embodiment, the reduced compounds include ethanol, succinate, lactate, a vitamin, a pharmaceutical and a biodegraded organic molecule. The NADH recycling system effects metabolic flux of reductive pathways in aerobic and anaerobic environments.

    摘要翻译: 本发明描述了一种用作生产还原化合物的方法的新型重组NADH再循环系统。 在具体实施方案中,还原的化合物包括乙醇,琥珀酸盐,乳酸盐,维生素,药物和生物降解的有机分子。 NADH回收系统在有氧和厌氧环境中影响还原途径的代谢通量。