公开(公告)号：US08581176B2

公开(公告)日：2013-11-12

申请号：US12788403

申请日：2010-05-27

Applicant: Bruce Thomson ,  Suzanne Ackloo

Inventor： Bruce Thomson ,  Suzanne Ackloo

IPC: H01J49/00

CPC classification number: H01J49/004 ,  G01N30/02 ,  G01N30/7233 ,  B01D15/34

Abstract: A system and method for performing MS/MS of everything are provided. Ionisable materials separated in order of molecular weight in a plurality of mass ranges are received at a mass spectrometer system in a given order in time, each mass range comprising a respective center mass value and a respective width. The ionisable materials are ionised in the given order that each of the plurality of mass ranges are received, to form respective precursor ions in a respective given mass range. The respective precursor ions are filtered via a mass filter module, a mass scan range of the mass filter module synchronized with the given order in which each of the plurality of mass ranges are received. The respective precursor ions are fragmented, via a fragmentation module, to form respective product ions. The respective product ions are analyzed in a mass spectrometer module to produce product ion spectra.

Abstract translation: 提供了一种用于执行MS / MS的一切的系统和方法。 在质谱仪系统中按照给定的时间顺序接收在多个质量范围内以分子量分级分离的可离子化材料，每个质量范围包括相应的中心质量值和相应的宽度。 可电离材料以给定的顺序电离，以便接收多个质量范围中的每一个，以在相应的给定质量范围内形成相应的前体离子。 通过质量过滤器模块过滤各个前体离子，质量过滤器模块的质量扫描范围与其中接收多个质量范围中的每一个的给定顺序同步。 各自的前体离子通过碎片模块被分段，以形成相应的产物离子。 在质谱仪模块中分析各产物离子以产生产物离子光谱。

公开(公告)号：US20110127419A1

公开(公告)日：2011-06-02

申请号：US12788403

申请日：2010-05-27

Applicant: Bruce Thomson ,  Suzanne Ackloo

Inventor： Bruce Thomson ,  Suzanne Ackloo

IPC: H01J49/00 ,  B01D59/44

CPC classification number: H01J49/004 ,  G01N30/02 ,  G01N30/7233 ,  B01D15/34

Abstract: A system and method for performing MS/MS of everything are provided. Ionisable materials separated in order of molecular weight in a plurality of mass ranges are received at a mass spectrometer system in a given order in time, each mass range comprising a respective center mass value and a respective width. The ionisable materials are ionised in the given order that each of the plurality of mass ranges are received, to form respective precursor ions in a respective given mass range. The respective precursor ions are filtered via a mass filter module, a mass scan range of the mass filter module synchronized with the given order in which each of the plurality of mass ranges are received. The respective precursor ions are fragmented, via a fragmentation module, to form respective product ions. The respective product ions are analyzed in a mass spectrometer module to produce product ion spectra.

Abstract translation: 提供了一种用于执行MS / MS的一切的系统和方法。 在质谱仪系统中按照给定的时间顺序接收在多个质量范围内以分子量分级分离的可离子化材料，每个质量范围包括相应的中心质量值和相应的宽度。 可电离材料以给定的顺序电离，以便接收多个质量范围中的每一个，以在相应的给定质量范围内形成相应的前体离子。 通过质量过滤器模块过滤各个前体离子，质量过滤器模块的质量扫描范围与其中接收多个质量范围中的每一个的给定顺序同步。 各自的前体离子通过碎片模块被分段，以形成相应的产物离子。 在质谱仪模块中分析各产物离子以产生产物离子光谱。