公开(公告)号：US5976871A

公开(公告)日：1999-11-02

申请号：US69560

申请日：1998-04-29

申请人： Richard Walker ,  Andrew Veldt ,  Kevin Ewing ,  Daniel Dorn ,  Jack L. Spurbeck ,  Syed M. Jalal

发明人： Richard Walker ,  Andrew Veldt ,  Kevin Ewing ,  Daniel Dorn ,  Jack L. Spurbeck ,  Syed M. Jalal

IPC分类号： B01L1/04 ,  C12M1/00 ,  G01N1/31 ,  C12M1/02

CPC分类号： G01N1/31 ,  B01L1/04 ,  Y10S435/809

摘要： The cytogenetic chamber includes a chamber enclosure, a drying cavity in the enclosure, a door and a hand-insertion port through the door. A slide-supported, fixative-treated cell (prepared outside the chamber or in situ in the chamber) is in the drying area and air flows through the entirety of the drying area at a substantially uniform (and relatively low) flow rate. The fixative dries at substantially the same drying rate, irrespective of the location of the slide in the drying area. The invention is particularly useful for chromosome spreading and results in a significantly-increased percentage of metaphases having metaphase areas in the optimal range of 2,500 to 4,500 squared microns.

摘要翻译： 细胞遗传室包括腔室，外壳中的干燥腔，门和通过门的手插入口。 载玻片支撑的固定处理的细胞（在室外或室内原位制备）处于干燥区域中，并且空气以基本上均匀（且相对低的）流速流过整个干燥区域。 固定剂以基本上相同的干燥速率干燥，而与干燥区域中载玻片的位置无关。 本发明对于染色体扩散特别有用，并且导致具有在2,500至4500平方微米的最佳范围内具有中期区域的中期百分比显着增加。

公开(公告)号：US5851790A

公开(公告)日：1998-12-22

申请号：US886981

申请日：1997-07-02

申请人： Richard Walker ,  Andrew Veldt ,  Kevin Ewing ,  Daniel Dorn ,  Jack L. Spurbeck ,  Syed M. Jalal

发明人： Richard Walker ,  Andrew Veldt ,  Kevin Ewing ,  Daniel Dorn ,  Jack L. Spurbeck ,  Syed M. Jalal

IPC分类号： B01L1/04 ,  C12M1/00 ,  G01N1/28 ,  G01N1/31 ,  G02B21/34

CPC分类号： G01N1/31 ,  B01L1/04 ,  G01N1/28 ,  Y10S435/809 ,  Y10T436/2525

摘要： The cytogenetic chamber includes a chamber enclosure, a drying cavity in the enclosure, a door and a hand-insertion port through the door. A slide-supported, fixative-treated cell (prepared outside the chamber or in situ in the chamber) is in the drying area and air flows through the entirety of the drying area at a substantially uniform (and relatively low) flow rate. The fixative dries at substantially the same drying rate, irrespective of the location of the slide in the drying area. A related method is also disclosed. The invention is particularly useful for chromosome spreading and results in a significantly-increased percentage of metaphases having metaphase areas in the optimal range of 2,500 to 4,500 squared microns.

摘要翻译： 细胞遗传室包括腔室，外壳中的干燥腔，门和通过门的手插入口。 载玻片支撑的固定处理的细胞（在室外或室内原位制备）处于干燥区域，空气以基本上均匀（且相对较低）的流速流过整个干燥区域。 固定剂以基本上相同的干燥速率干燥，而与干燥区域中载玻片的位置无关。 还公开了相关方法。 本发明对于染色体扩散特别有用，并且导致具有在2,500至4500平方微米的最佳范围内具有中期区域的中期百分比显着增加。