公开(公告)号：US20230390306A1

公开(公告)日：2023-12-07

申请号：US18031749

申请日：2021-10-12

Applicant: THERAMEX HQ UK LIMITED

Inventor： Mitra BOOLELL

IPC: A61K31/573 ,  A61K9/00 ,  A61K31/565 ,  A61P15/18 ,  A61K31/567

CPC classification number: A61K31/573 ,  A61K9/0053 ,  A61K31/565 ,  A61P15/18 ,  A61K31/567

Abstract: Provided are methods of contraception using as a first line combined oral contraceptive (COC), a COC composition comprising nomegestrol acetate (NOMAC) and estradiol or an ester thereof. Said COC compositions are associated with a lower risk of venous thromboembolism (VTE) as compared to other CHCs. The compositions may also be used in methods of treatment in women having conditions linked to menstruation and/or fertility.

公开(公告)号：US20230398127A1

公开(公告)日：2023-12-14

申请号：US18031748

申请日：2021-10-12

Applicant: THERAMEX HQ UK LIMITED

Inventor： Mitra BOOLELL

IPC: A61K31/565 ,  A61K31/57 ,  A61K9/00 ,  A61P7/02

CPC classification number: A61K31/565 ,  A61K31/57 ,  A61K9/0053 ,  A61P7/02

Abstract: The present invention relates to the use of compositions comprising nomegestrol acetate (NOMAC) and estradiol or an ester thereof. The compositions are for use in reducing the risk of venous thromboembolism (VTE) associated with the use of combined oral contraceptives (COC). The compositions may be used in methods of contraception and/or methods of treatment in women having conditions linked to menstruation and/or fertility.