公开(公告)号：US20190099382A1

公开(公告)日：2019-04-04

申请号：US16087557

申请日：2017-03-23

Applicant: TOYO UNIVERSITY

Inventor： Toru MAEKAWA ,  Sakthikumar DASAPPAN NAIR ,  Sheikh Mohamed MOHAMED ,  Srivani VEERANARAYANAN

IPC: A61K9/51 ,  A61K47/24 ,  A61K47/12 ,  A61K47/10 ,  A61K47/42 ,  A61K38/16 ,  A61P35/00

Abstract: Provided is a composition which can be utilized for drug delivery systems that can penetrate the blood brain barrier, and has low cytotoxicity. A nanoparticle composition comprises nanoparticles to the surface of which a first substance and a second substance each having specificity to a tumor cell are bound, wherein the first substance having specificity to the tumor cell is a peptide comprising an amino acid sequence of arginine-glycine-aspartic acid, and wherein the second substance having specificity to the tumor cell is an iron-binding protein, and wherein the nanoparticles each comprise an outer layer and vesicles enveloped by the outer layer and the nanoparticles each comprise, as membrane components, a PEGylated phospholipid, a fatty acid with a melting point of 30° C. or more, and a non-PEGylated phospholipid.

公开(公告)号：US20160183848A1

公开(公告)日：2016-06-30

申请号：US14979669

申请日：2015-12-28

Applicant: TOYO UNIVERSITY

Inventor： Hideo KAWAGUCHI

IPC: A61B5/11

CPC classification number: A61B5/1124 ,  A61B5/1126 ,  A61B5/4082 ,  A61B5/4094 ,  A61B2562/0219

Abstract: A motor performance evaluation apparatus 100 for evaluating motor performance of a subject, including: an acquisition unit 131 configured to acquire drawing stroke information including position information and time information on drawing stroke of the subject copying a predetermined single-stroke drawn figure; a detection unit 132 configured to detect a fall count indicating the number of times a drawing acceleration of the subject changes from a positive value to a negative value, based on the drawing stroke information; and an evaluation unit 133 configured to evaluate the motor performance of the subject, based on the fall count.

Abstract translation: 一种用于评估被摄体的电动机性能的电动机性能评估装置100，包括：获取单元131，其被构造成获取包括位置信息的绘制笔画信息和关于绘制描绘预定单笔绘制图形的对象的笔画的时间信息; 检测单元132，被配置为基于绘图笔画信息检测指示被摄体的绘制加速度从正值变化到负值的次数的下降计数; 以及评估单元133，其被配置为基于所述下降计数来评估所述对象的电动机性能。

公开(公告)号：US20140303522A1

公开(公告)日：2014-10-09

申请号：US14361079

申请日：2012-11-29

Applicant: TOYO UNIVERSITY

Inventor： Toshinari Akimoto ,  Nobuyuki Terada

IPC: A61B5/00 ,  A61B6/00 ,  A61B5/107

CPC classification number: A61B5/4566 ,  A61B5/0002 ,  A61B5/1077 ,  A61B5/1079 ,  A61B5/4561 ,  A61B5/7282 ,  A61B5/742 ,  A61B5/743 ,  A61B6/505

Abstract: The scoliosis evaluation system comprises a 3D sensor (100) that takes the back of a subject and acquires the 3D data thereon; a characteristic part designator (102) that designates a characteristic part of which the degree of curvature is to be measured on the back of the subject, an uneven state detector (103) that detects an uneven state of a body surface in a horizontal direction based on the 3D data on the characteristic part designated by the characteristic part designator, and a display monitor (200) that displays a result detected by the uneven state detector.

Abstract translation: 脊柱侧凸评估系统包括：3D传感器（100），其获取对象的背部并在其上获取3D数据; 指定要在被检体背面测量曲率的特征部分的特征部分标识符（102），基于水平方向检测身体表面的不均匀状态的不平坦状态检测器（103） 关于由特征部件指示器指定的特征部分上的3D数据，以及显示由不均匀状态检测器检测到的结果的显示监视器（200）。

公开(公告)号：US20250030010A1

公开(公告)日：2025-01-23

申请号：US18580811

申请日：2022-07-08

Applicant: TOYO UNIVERSITY

Inventor： Mika GAMO

IPC: H01M4/92 ,  H01M4/88 ,  H01M8/1004

Abstract: The present invention relates to a novel electrode material for fuel cells, and more particularly, to an electrode material for fuel cells, the electrode material comprising carbon fibers, in which the carbon fibers are carbon fibers covered with fibrous nanocarbon that supports a catalyst metal.

公开(公告)号：US12176548B2

公开(公告)日：2024-12-24

申请号：US17618185

申请日：2020-07-01

Applicant: TOYO UNIVERSITY

Inventor： Noboru Wada

IPC: H01M8/086 ,  H01M4/86 ,  H01M4/90 ,  H01M8/1018

Abstract: Provided is a fuel cell catalyst composition comprising a C12A7:X− inorganic material having a structure in which oxygen anions of C12A7 are replaced by halogen (X) anions, or comprising a C12A7:X−-based inorganic material which is a C12A7:X− partially converted to electride. A fuel cell comprising the fuel cell catalyst composition in a catalyst layer is also provided. Also provided is a method of producing a fuel cell catalyst composition, comprising a step of heat-treating C12A7:X− at temperature of 1000-1300° C. for at least 20 hours under a nitrogen atmosphere.

公开(公告)号：US20210087091A1

公开(公告)日：2021-03-25

申请号：US16772266

申请日：2018-12-13

Applicant: TOYO UNIVERSITY ,  TOYO TANSO CO., LTD.

Inventor： Tatsuo SUMINO ,  Satoshi SAKUMA ,  Tetsuro TOJO ,  Ai ISHIKAWA ,  Tomoya NAKAZONO ,  Masatoshi TAKESHITA

IPC: C02F3/34 ,  C02F3/30

Abstract: [Problem] A carrier for retaining anammox bacteria, an anammox bacteria-adhered particle, and a wastewater treatment apparatus are provided that can remarkably reduce the start-up period for obtaining a nitrogen removal speed of 1 kg-N/m3/day.
[Solution] A carrier for retaining anammox bacteria includes carbon particles. The carbon particles are desirably graphite particles, particularly isotropic graphite particles. The carbon particles desirably have a zeta potential of −35 mV to 0 mV and an average particle size of 2 μm to 1000 μm.

公开(公告)号：US20200297694A1

公开(公告)日：2020-09-24

申请号：US16650615

申请日：2018-09-26

Applicant: TOYO UNIVERSITY

Inventor： Kazunori KATO

IPC: A61K31/366 ,  A61K31/353 ,  A61K31/20 ,  A61K36/752 ,  A23L33/105 ,  A23L33/12 ,  A23K20/126 ,  A23K20/158

Abstract: This application provides a composition for preventing, alleviating and/or treating a heat illness, or cytotoxicity of cells such as vascular endothelial cells caused by load of heat stress and/or aberration associated with the production and release of a fever-inducing inflammatory cytokine(s) from blood cells caused by load of heat stress in a subject, comprising at least one substance selected from the group consisting of auraptene, tangeretin, and medium chain fatty acid as an active ingredient.

公开(公告)号：US20230271006A1

公开(公告)日：2023-08-31

申请号：US18169319

申请日：2023-02-15

Applicant: SUMIDA CORPORATION ,  TOYO UNIVERSITY

Inventor： Tsunaki KANEKO ,  Masaki SAITO ,  Thitaporn DETMOD ,  Kenji TERAO ,  Masafumi OHSAKO ,  Xueqian ZENG

IPC: A61N1/36

CPC classification number: A61N1/36014 ,  A61N1/36034

Abstract: Provided is a method for treating a living body using an electrical stimulator including a base wire having a core wire and an outer winding wire wound around the core wire. An annulus is formed by winding the base wire in a loop shape. A first end of the core wire is electrically connected to a first end of the outer winding wire. A second end of the core wire is connected to a first terminal of an external circuit. A second end of the outer winding wire is connected to a second terminal of the external circuit. The method includes holding the living body or a part of the living body of a subject in the annulus and generating an alternating current in the external circuit for a therapeutically effective time period to apply an electrical stimulation to the living body or the part of the living body.

公开(公告)号：US11559512B2

公开(公告)日：2023-01-24

申请号：US16650615

申请日：2018-09-26

Applicant: TOYO UNIVERSITY

Inventor： Kazunori Kato

IPC: A61K36/752 ,  A61K31/366 ,  A23K20/126 ,  A23K20/158 ,  A23L33/12 ,  A23L33/105 ,  A61K31/20 ,  A61K31/353

Abstract: This application provides a composition for preventing, alleviating and/or treating a heat illness, or cytotoxicity of cells such as vascular endothelial cells caused by load of heat stress and/or aberration associated with the production and release of a fever-inducing inflammatory cytokine(s) from blood cells caused by load of heat stress in a subject, comprising at least one substance selected from the group consisting of auraptene, tangeretin, and medium chain fatty acid as an active ingredient.

公开(公告)号：US20220271297A1

公开(公告)日：2022-08-25

申请号：US17618185

申请日：2020-07-01

Applicant: TOYO UNIVERSITY

Inventor： Noboru WADA

IPC: H01M4/90 ,  H01M4/86 ,  H01M8/086 ,  H01M8/1018

Abstract: Provided is a fuel cell catalyst composition comprising a C12A7:X− inorganic material having a structure in which oxygen anions of C12A7 are replaced by halogen (X) anions, or comprising a C12A7:X−-based inorganic material which is a C12A7:X− partially converted to electride. A fuel cell comprising the fuel cell catalyst composition in a catalyst layer is also provided. Also provided is a method of producing a fuel cell catalyst composition, comprising a step of heat-treating C12A7:X− at temperature of 1000-1300° C. for at least 20 hours under a nitrogen atmosphere.