公开(公告)号：US20210338599A1

公开(公告)日：2021-11-04

申请号：US17174947

申请日：2021-02-12

申请人： TRS II, LLC

发明人： Ted SCHWARZROCK ,  Gary CLEARY

IPC分类号： A61K9/70 ,  A61K31/593 ,  A61K31/592 ,  A61K31/59 ,  A61K47/10 ,  A61K47/14

摘要： The invention provides compositions and methods for delivering vitamin D to a human subject. In one embodiment the invention provides a transdermal patch for the transdermal administration of vitamin D comprising: (a) a backing layer that serves as the outer surface of the patch during use; (b) an adhesive drug reservoir layer for affixing the patch to human skin; and (c) a release liner, which upon removal exposes the adhesive drug reservoir layer. The adhesive drug reservoir layer can include vitamin D, a polymeric adhesive, an organic solvent, and a permeation enhancer.

公开(公告)号：US20180169034A1

公开(公告)日：2018-06-21

申请号：US15736651

申请日：2016-06-14

申请人： TRS II, LLC

发明人： Ted SCHWARZROCK ,  Gary CLEARY

IPC分类号： A61K9/70 ,  A61K47/14 ,  A61K47/10 ,  A61K31/593 ,  A61K31/592

CPC分类号： A61K9/7061 ,  A61K9/7046 ,  A61K9/7069 ,  A61K31/59 ,  A61K31/592 ,  A61K31/593 ,  A61K47/10 ,  A61K47/14

摘要： The invention provides compositions and methods for delivering vitamin D to a human subject. In one embodiment the invention provides a transdermal patch for the transdermal administration of vitamin D comprising: (a) a backing layer that serves as the outer surface of the patch during use; (b) an adhesive drug reservoir layer for affixing the patch to human skin; and (c) a release liner, which upon removal exposes the adhesive drug reservoir layer. The adhesive drug reservoir layer can include vitamin D, a polymeric adhesive, an organic solvent, and a permeation enhancer.

公开(公告)号：US20240197647A1

公开(公告)日：2024-06-20

申请号：US18520143

申请日：2023-11-27

申请人： TRS II, LLC

发明人： Ted SCHWARZROCK ,  Gary CLEARY

IPC分类号： A61K9/70 ,  A61K31/59 ,  A61K31/592 ,  A61K31/593 ,  A61K47/10 ,  A61K47/14

CPC分类号： A61K9/7061 ,  A61K9/7046 ,  A61K9/7069 ,  A61K31/59 ,  A61K31/592 ,  A61K31/593 ,  A61K47/10 ,  A61K47/14

摘要： Compositions and methods for delivering vitamin D to a subject. In one embodiment the invention provides a transdermal patch for the transdermal administration of vitamin D comprising: (a) a backing layer that serves as the outer surface of the patch during use; (b) an adhesive drug reservoir layer for affixing the patch to skin; and (c) a release liner, which upon removal exposes the adhesive drug reservoir layer. The adhesive drug reservoir layer can include vitamin D, a polymeric adhesive, an organic solvent, and a permeation enhancer.

公开(公告)号：US11826478B2

公开(公告)日：2023-11-28

申请号：US17174947

申请日：2021-02-12

申请人： TRS II, LLC

发明人： Ted Schwarzrock ,  Gary Cleary

IPC分类号： A61K31/593 ,  A61K47/10 ,  A61K47/14 ,  A61K9/70 ,  A61K31/592 ,  A61K31/59

CPC分类号： A61K9/7061 ,  A61K9/7046 ,  A61K9/7069 ,  A61K31/59 ,  A61K31/592 ,  A61K31/593 ,  A61K47/10 ,  A61K47/14

摘要： The invention provides compositions and methods for delivering vitamin D to a human subject. In one embodiment the invention provides a transdermal patch for the transdermal administration of vitamin D comprising: (a) a backing layer that serves as the outer surface of the patch during use; (b) an adhesive drug reservoir layer for affixing the patch to human skin; and (c) a release liner, which upon removal exposes the adhesive drug reservoir layer. The adhesive drug reservoir layer can include vitamin D, a polymeric adhesive, an organic solvent, and a permeation enhancer.