公开(公告)号：US20070212372A1

公开(公告)日：2007-09-13

申请号：US11799862

申请日：2007-05-03

申请人： Kylie Shipham ,  Tamara Bucci ,  Helmut Butzkueven ,  Trevor Kilpatrick ,  Perry Bartlett ,  Merja Soilu-Hanninen

发明人： Kylie Shipham ,  Tamara Bucci ,  Helmut Butzkueven ,  Trevor Kilpatrick ,  Perry Bartlett ,  Merja Soilu-Hanninen

IPC分类号： A61K39/00

CPC分类号： C07K14/4703 ,  A61K38/2093

摘要： The present invention relates to a method for the treatment and/or prophylaxis of a nervous system disease, demyelinating disease and/or an inflammatory disease of either the central or peripheral nervous system such as but not limited to an encephalopathic condition and even more particularly an encephalomyelopathic condition. The present invention further provides the use of leukemia inhibitory factor or derivatives, homologues or analogues thereof in the treatment and/or prophylaxis of a nervous system disease, demyelinating disease and/or an inflammatory disease of either the central or peripheral nervous system. Leukemia inhibitory factor may be used alone or in combination with one or more other therapeutic molecules.

摘要翻译： 本发明涉及用于治疗和/或预防神经系统疾病，脱髓鞘疾病和/或中枢神经系统或周围神经系统的炎性疾病的方法，例如但不限于脑病，甚至更特别地， 脑炎病情。 本发明还提供了白血病抑制因子或其衍生物，同系物或类似物在治疗和/或预防神经系统疾病，脱髓鞘疾病和/或中枢神经系统或周围神经系统的炎性疾病中的用途。 白血病抑制因子可以单独使用或与一种或多种其它治疗分子组合使用。