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公开(公告)号:US20130096097A1
公开(公告)日:2013-04-18
申请号:US13702205
申请日:2011-06-07
申请人: Hitoshi Kasai , Hachiro Nakanishi , Koichi Baba , Hidetoshi Oikawa , Tastuya Murakami , Hiroshi Imahori , Misturu Hashida , Isamu Oh
发明人: Hitoshi Kasai , Hachiro Nakanishi , Koichi Baba , Hidetoshi Oikawa , Tastuya Murakami , Hiroshi Imahori , Misturu Hashida , Isamu Oh
IPC分类号: A61K9/10
CPC分类号: A61K9/10 , A61K9/5123 , A61K31/4745 , A61K31/573 , A61K47/55
摘要: [Problem] The purpose of the present invention is to provide organic particles containing pharmaceutical particles of which the particles are small and the particle size distribution is narrow, and a manufacturing method for the same.[Solution] Provided are pharmaceutical multimeric particles of which the particles are small and the particle size distribution is narrow and which are characterized in being obtained by pouring into water a solution of a pharmaceutical multimer dissolved in a water-miscible organic solvent, and a manufacturing method for the pharmaceutical multimeric particles. Pharmaceutical dimeric particles thereof are characterized in being obtained by pouring into water a solution of a compound represented by general formula (I) dissolved in a water-miscible organic solvent.
摘要翻译: 本发明的目的是提供含有粒子小,粒径分布狭窄的药物粒子的有机粒子及其制造方法。 [解决方案]提供了颗粒小且粒度分布窄的药物多聚体颗粒,其特征在于通过将溶解在水混溶性有机溶剂中的药物多聚体的溶液倒入水中而获得, 药物多聚体颗粒的方法。 其特征在于通过将溶解在与水可混溶的有机溶剂中的通式(I)表示的化合物的溶液倒入水中而获得的药物二聚体颗粒。