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公开(公告)号:US20100196962A1
公开(公告)日:2010-08-05
申请号:US12407170
申请日:2009-03-19
申请人: Teiji EKIDA , Harutaka Yagame , Hiroshi Iida , Kiyoshi Yasukawa , Shigeo Tsuchiya , Teruhiko Ide
发明人: Teiji EKIDA , Harutaka Yagame , Hiroshi Iida , Kiyoshi Yasukawa , Shigeo Tsuchiya , Teruhiko Ide
CPC分类号: C12N5/0647 , A61K38/00 , C07K14/5412 , C07K14/7155 , C07K2319/00 , C12N2501/125
摘要: The present invention intends to provide an IL-6R.IL-6 fusion protein and the like in which IL-6R and IL-6 are directly linked without a linker.The IL-6 receptor.IL-6 fusion protein of the present invention has a structure in which one amino acid residue constituting IL-6 receptor and one amino acid residue constituting IL-6 are directly bonded.
摘要翻译: 本发明意图提供IL-6R.IL-6融合蛋白等,其中IL-6R和IL-6直接连接而不连接。 本发明的IL-6受体-IL-6融合蛋白具有构成IL-6受体的一个氨基酸残基和构成IL-6的一个氨基酸残基直接结合的结构。
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公开(公告)号:US07901911B2
公开(公告)日:2011-03-08
申请号:US12407170
申请日:2009-03-19
申请人: Teiji Ekida , Harutaka Yagame , Hiroshi Iida , Kiyoshi Yasukawa , Shigeo Tsuchiya , Teruhiko Ide
发明人: Teiji Ekida , Harutaka Yagame , Hiroshi Iida , Kiyoshi Yasukawa , Shigeo Tsuchiya , Teruhiko Ide
CPC分类号: C12N5/0647 , A61K38/00 , C07K14/5412 , C07K14/7155 , C07K2319/00 , C12N2501/125
摘要: The present invention intends to provide an IL-6R.IL-6 fusion protein and the like in which IL-6R and IL-6 are directly linked without a linker.The IL-6 receptor.IL-6 fusion protein of the present invention has a structure in which one amino acid residue constituting IL-6 receptor and one amino acid residue constituting IL-6 are directly bonded.
摘要翻译: 本发明意图提供IL-6R.IL-6融合蛋白等,其中IL-6R和IL-6直接连接而不连接。 本发明的IL-6受体-IL-6融合蛋白具有构成IL-6受体的一个氨基酸残基和构成IL-6的一个氨基酸残基直接键合的结构。
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公开(公告)号:US07531644B2
公开(公告)日:2009-05-12
申请号:US11544639
申请日:2006-10-10
申请人: Teiji Ekida , Harutaka Yagame , Hiroshi Iida , Kiyoshi Yasukawa , Shigeo Tsuchiya , Teruhiko Ide
发明人: Teiji Ekida , Harutaka Yagame , Hiroshi Iida , Kiyoshi Yasukawa , Shigeo Tsuchiya , Teruhiko Ide
IPC分类号: C07K14/52 , C07K14/705
CPC分类号: C12N5/0647 , A61K38/00 , C07K14/5412 , C07K14/7155 , C07K2319/00 , C12N2501/125
摘要: The present invention intends to provide an IL-6R•IL-6 fusion protein and the like in which IL-6R and IL-6 are directly linked without a linker.The IL-6 receptor•IL-6 fusion protein of the present invention has a structure in which one amino acid residue constituting IL-6 receptor and one amino acid residue constituting IL-6 are directly bonded.
摘要翻译: 本发明意图提供IL-6R.IL-6融合蛋白等,其中IL-6R和IL-6直接连接而不连接。 本发明的IL-6受体-IL-6融合蛋白具有构成IL-6受体的一个氨基酸残基和构成IL-6的一个氨基酸残基直接结合的结构。
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公开(公告)号:US20070031376A1
公开(公告)日:2007-02-08
申请号:US11544639
申请日:2006-10-10
申请人: Teiji Ekida , Harutaka Yagame , Hiroshi Iida , Kiyoshi Yasukawa , Shigeo Tsuchiya , Teruhiko Ide
发明人: Teiji Ekida , Harutaka Yagame , Hiroshi Iida , Kiyoshi Yasukawa , Shigeo Tsuchiya , Teruhiko Ide
CPC分类号: C12N5/0647 , A61K38/00 , C07K14/5412 , C07K14/7155 , C07K2319/00 , C12N2501/125
摘要: The present invention intends to provide an IL-6R•IL-6 fusion protein and the like in which IL-6R and IL-6 are directly linked without a linker. The IL-6 receptor•IL-6 fusion protein of the present invention has a structure in which one amino:acid residue constituting IL-6 receptor and one amino acid residue constituting IL-6 are directly bonded.
摘要翻译: 本发明意图提供IL-6R.IL-6融合蛋白等,其中IL-6R和IL-6直接连接而不连接。 本发明的IL-6受体-IL-6融合蛋白具有构成IL-6受体的一个氨基酸残基和构成IL-6的一个氨基酸残基直接结合的结构。
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