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公开(公告)号：US20240225832A9
公开(公告)日：2024-07-11
申请号：US18486131
申请日：2023-10-12
发明人： Amy Marie Danielson
IPC分类号： A61F2/24
CPC分类号： A61F2/243 , A61F2220/0016
摘要： An epicardial anchor device may include a base defining a radial slot, and a top component including a first piece and a second piece each operably coupled to the base. The first piece may include a first recess and the second piece may include a second recess. The epicardial anchor device may have (i) an unpinned condition in which the first piece and the second piece are spaced from each other a first distance so that a tether may be laterally slid within the radial slot and between the first piece and the second piece, and (ii) a pinned condition in which the first piece and the second piece are spaced from each other a second distance so that the tether may be confined within an aperture defined by the first recess and the second recess, the second distance being smaller than the first distance.
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2.发明授权公开(公告)号：US11759318B2
公开(公告)日：2023-09-19
申请号：US15874746
申请日：2018-01-18
发明人： Robert Vidlund
CPC分类号： A61F2/2418 , A61F2/2439 , A61F2/2457 , A61F2002/9534 , A61F2220/0008 , A61F2250/0003 , A61F2250/006 , A61F2250/0069
摘要： This invention relates to the design and function of a device which allows for retrieval of a previously implanted valve prosthesis from a beating heart without extracorporeal circulation using a transcatheter retrieval system, including a guide component to facilitate the compression of the valve and retraction into a retrieval catheter, as well as an improved prosthetic transcatheter heart valve having one or more of: a series of radially extending tines having a loop terminus to improve sealing a deployed prosthetic mitral valve against hemodynamic leaking, a pre-compressible stent-in-stent design, or an articulating cuff attached to a covered stent-valve and a commissural sealing skirt structure attached to the underside of the articulating cuff.
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公开(公告)号：US11589985B2
公开(公告)日：2023-02-28
申请号：US16233363
申请日：2018-12-27
摘要： Apparatus and methods are described herein for use in the transfemoral delivery and deployment of a prosthetic mitral valve. In some embodiments, a method includes inverting an outer frame of a prosthetic mitral valve when in a biased expanded configuration. After inverting the outer frame, the prosthetic mitral valve is inserted into a lumen of a delivery sheath such that the mitral valve is moved to a collapsed configuration. The delivery sheath is inserted into a femoral vein and moved through the femoral vein and a septum of a heart until a distal end of the delivery sheath is disposed in the left atrium of the heart. The prosthetic mitral valve is moved distally out of the delivery sheath such that the inverted outer frame reverts and the prosthetic mitral valve assumes its biased expanded configuration. The prosthetic mitral valve is then positioned within a mitral annulus of the heart.
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公开(公告)号：US20230000626A1
公开(公告)日：2023-01-05
申请号：US17931787
申请日：2022-09-13
发明人： Mark Christianson , Chad Perrin , Zachary Tegels , Craig Ekvall , Robert Vidlund , Son Mai , Michael Evans
IPC分类号： A61F2/24
摘要： A prosthetic heart valve can include an outer support assembly, an inner valve assembly, which define between them an annular space, and a pocket closure that bounds the annular space to form a pocket in which thrombus can be formed and retained. Alternatively, or additionally, the outer support assembly and the inner valve assembly can be coupled at the ventricle ends of the outer support assembly and the inner valve assembly, with the outer support assembly being relatively more compliant in hoop compression in a central, annulus portion than at the ventricle end, so that the prosthetic valve can seat securely in the annulus while imposing minimal loads on the inner valve assembly that could degrade the performance of the valve leaflets.
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公开(公告)号：US11471281B2
公开(公告)日：2022-10-18
申请号：US16776687
申请日：2020-01-30
发明人： Mark Christianson , Chad Perrin , Zachary Tegels , Craig Ekvall , Robert Vidlund , Son Mai , Michael Evans
IPC分类号： A61F2/24
摘要： A prosthetic heart valve can include an outer support assembly, an inner valve assembly, which define between them an annular space, and a pocket closure that bounds the annular space to form a pocket in which thrombus can be formed and retained. Alternatively, or additionally, the outer support assembly and the inner valve assembly can be coupled at the ventricle ends of the outer support assembly and the inner valve assembly, with the outer support assembly being relatively more compliant in hoop compression in a central, annulus portion than at the ventricle end, so that the prosthetic valve can seat securely in the annulus while imposing minimal loads on the inner valve assembly that could degrade the performance of the valve leaflets.
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公开(公告)号：US20220313427A1
公开(公告)日：2022-10-06
申请号：US17691307
申请日：2022-03-10
发明人： Zachary R. Vidlund
IPC分类号： A61F2/24
摘要： A system comprising a prosthetic heart valve having a frame, prosthetic leaflets within the frame configured to allow blood to flow through the prosthetic heart valve in an antegrade direction but to substantially block blood from flowing through the prosthetic heart valve in a retrograde direction, an anchor configured to be secured against a ventricular apex of a heart of a patient, a tether coupled to the frame and through the anchor, and an end of the tether configured to extend beyond the anchor when the tether is fixed to the anchor, and a tether adjustment member having a collapsible tube defining an open leading end configured to receive the second end of the tether, and a wire leader extending from a second trailing end of the tube.
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7.发明授权公开(公告)号：US11382753B2
公开(公告)日：2022-07-12
申请号：US16681282
申请日：2019-11-12
发明人： Craig A. Ekvall , Robert M. Vidlund
摘要： Apparatus and methods are described herein for positioning an epicardial anchor device and measuring the load of a tether extending from a prosthetic heart valve and coupled to the epicardial anchor device. In some embodiments, an apparatus includes a handle assembly coupled to an elongate member and a docking member coupled to a distal end of the elongate member. The docking member can be releasably coupled to an epicardial anchor device configured to secure a tether extending from a prosthetic heart valve implanted with a heart at a location on an exterior of a ventricular wall of the heart. A force sensor device is coupled to the handle assembly and can measure a force exerted on the force sensor device. The force is associated with a tension of the tether extending through the elongate member and handle assembly.
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公开(公告)号：US11364116B2
公开(公告)日：2022-06-21
申请号：US17402704
申请日：2021-08-16
摘要： This invention relates to the design and function of a compressible valve replacement prosthesis, collared or uncollared, which can be deployed into a beating heart without extracorporeal circulation using a transcatheter delivery system. The design as discussed focuses on the deployment of a device via a minimally invasive fashion and by way of example considers a minimally invasive surgical procedure preferably utilizing the intercostal or subxyphoid space for valve introduction. In order to accomplish this, the valve is formed in such a manner that it can be compressed to fit within a delivery system and secondarily ejected from the delivery system into the annulus of a target valve such as a mitral valve or tricuspid valve.
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公开(公告)号：US11006939B2
公开(公告)日：2021-05-18
申请号：US16212781
申请日：2018-12-07
发明人： Zachary Vidlund
摘要： In some embodiments, an apparatus includes an introducer sheath and a dilator. The introducer sheath can include a body portion and a tip portion. The body portion can be coupled to the tip portion via a seal portion. The dilator can be configured to be inserted into a lumen defined by the introducer sheath such that the dilator can engage with the tip portion and translate the tip portion relative to the body portion such that the tip portion moves the seal portion from a biased neutral configuration to an extended configuration for delivery of the apparatus to a location in a patient's body. The seal portion can have a larger outermost diameter in the neutral configuration than in the extended configuration.
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公开(公告)号：US20210030541A1
公开(公告)日：2021-02-04
申请号：US16935655
申请日：2020-07-22
发明人： Zachary R. Vidlund
摘要： Apparatus and methods are described herein for use in in establishing an improved AV loop with the use of a pulley/snare device at the base of a ventricle of a heart. In some methods described herein, a pulley/snare device is established to create a path with inherent concentricity to the aortic and mitral valves, allowing the valves to function normally during an interventional procedure in the heart, without impeding the motion of any leaflets. The pulley/snare device described herein minimizes the forces that are applied on the valves or associated cardiac tissue to “make the turn” from the aortic valve to the mitral valve.
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