公开(公告)号：US20240358509A1

公开(公告)日：2024-10-31

申请号：US18770297

申请日：2024-07-11

Applicant: EDWARDS LIFESCIENCES CORPORATION

Inventor： George Bakis ,  Thanh V. Nguyen ,  Ly Th Phan ,  Asher L. Metchik

IPC: A61F2/24

CPC classification number: A61F2/2436 ,  A61F2/2418 ,  A61F2/2439

Abstract: Certain embodiments of the present disclosure provide a prosthetic valve (e.g., prosthetic heart valve) and a valve delivery apparatus for delivery of the prosthetic valve to a native valve site via the human vasculature. The delivery apparatus is particularly suited for advancing a prosthetic heart valve through the aorta (i.e., in a retrograde approach) for replacing a diseased native aortic valve. The delivery apparatus in particular embodiments is configured to deploy a prosthetic valve from a delivery sheath in a precise and controlled manner at the target location within the body.

公开(公告)号：US20240358506A1

公开(公告)日：2024-10-31

申请号：US18769639

申请日：2024-07-11

Applicant: EDWARDS LIFESCIENCES CORPORATION

Inventor： Joseph Mordechai Leichner ,  Anatoly Dvorsky

IPC: A61F2/24

CPC classification number: A61F2/2418 ,  A61F2/2436 ,  A61F2250/0096

Abstract: The present invention relates to systems, assemblies and methods for detecting detachment of a prosthetic valve actuator. In an example, a prosthetic valve actuator detachment detection system comprises at least one actuator, a frame of the prosthetic valve movable by the at least one actuator between a radially compressed configuration and a radially expanded configuration, and at least one mechanical wave sensor.

公开(公告)号：US12127937B2

公开(公告)日：2024-10-29

申请号：US16405286

申请日：2019-05-07

Applicant: Medtentia International Ltd Oy

Inventor： Olli Keränen

IPC: A61F2/24

CPC classification number: A61F2/2409 ,  A61F2/2418 ,  A61F2/2427 ,  A61F2/2442 ,  A61F2/2445 ,  A61F2/2466 ,  A61F2230/0013 ,  A61F2230/008 ,  A61F2230/0091 ,  A61F2250/006

Abstract: The present disclosure relates to an arrangement, a loop-shaped support, a prosthetic heart valve and a method of repairing or replacing a native heart valve. With the method or the arrangement, leakage or regurgitation between a prosthetic heart valve and the surrounding valve tissue is prevented. In one embodiment, an arrangement for replacement or repair of a native heart valve is provided, which comprises a loop-shaped support 41 and a prosthetic heart valve 70 and wherein an outer segment 32 of the loop-shaped support 41 is positionable towards surrounding valve tissue of a native heart valve and wherein an outer surface 74 of the prosthetic heart valve 70 is positionable towards an inner segment 34 of the loop-shaped support 41 so as to prevent paravalvular leakage or regurgitation between the prosthetic heart valve 70 and the surrounding valve tissue of the native heart valve.

公开(公告)号：US20240350268A1

公开(公告)日：2024-10-24

申请号：US18753476

申请日：2024-06-25

Applicant: Evalve, Inc.

Inventor： Koji Kizuka ,  Richard Childs ,  Gabriel Gonzales ,  Dylan Van Hoven ,  Chad Abunassar ,  Travis Marsot ,  Rob Mosley ,  Nisu Patel ,  Francisco Valencia

IPC: A61F2/24

CPC classification number: A61F2/2439 ,  A61F2/2418 ,  A61F2210/0014 ,  A61F2220/0016 ,  A61F2250/0098

Abstract: Fixation system for fixation of leaflets of a heart valve including an implantable fixation device having a first arm and a second arm, a first proximal element moveable relative to the first arm between a first position and a second position, and a second proximal element moveable relative to the second arm between a first position and a second position. The fixation system includes a delivery device having a catheter, a first proximal element line and a second proximal element line, and a handle having a first and second proximal element line handles coupled to the first proximal element line and the second proximal element line, respectively. The handle can include an interlock moveable between an unlocked position and a locked position.

公开(公告)号：US12121434B2

公开(公告)日：2024-10-22

申请号：US17930661

申请日：2022-09-08

Applicant: Tendyne Holdings, Inc.

Inventor： Robert Vidlund ,  Kemal Schankereli ,  Lucian Lozonschi ,  Georg Lutter

IPC: A61F2/24 ,  A61L27/34 ,  A61L27/36 ,  A61L33/00 ,  C08L67/04 ,  A61B17/04 ,  A61B17/064

CPC classification number: A61F2/2412 ,  A61F2/2409 ,  A61F2/2418 ,  A61F2/2427 ,  A61L27/34 ,  A61L27/3625 ,  A61L27/3629 ,  A61L33/0011 ,  C08L67/04 ,  A61B17/0401 ,  A61B2017/0404 ,  A61B17/064 ,  A61B17/0644 ,  A61F2/2436 ,  A61F2/2457 ,  A61F2210/0004 ,  A61F2210/0014 ,  A61F2220/0008 ,  A61F2220/005 ,  A61F2220/0058 ,  A61F2220/0091 ,  A61F2230/0013 ,  A61F2230/0034 ,  A61F2230/005 ,  A61F2230/0054 ,  A61F2230/0067 ,  A61F2230/0091 ,  A61F2310/00023 ,  A61F2310/00077 ,  A61L2400/16 ,  A61L2430/20 ,  A61L27/34 ,  C08L67/04

Abstract: This invention relates to the design and function of a compressible valve replacement prosthesis, collared or uncollared, which can be deployed into a beating heart without extracorporeal circulation using a transcatheter delivery system. The design as discussed focuses on the deployment of a device via a minimally invasive fashion and by way of example considers a minimally invasive surgical procedure preferably utilizing the intercostal or subxyphoid space for valve introduction. In order to accomplish this, the valve is formed in such a manner that it can be compressed to fit within a delivery system and secondarily ejected from the delivery system into the annulus of a target valve such as a mitral valve or tricuspid valve.

公开(公告)号：US20240341955A1

公开(公告)日：2024-10-17

申请号：US18611353

申请日：2024-03-20

Applicant: Transmural Systems LLC

Inventor： Nasser Rafiee

IPC: A61F2/24 ,  A61B17/04 ,  A61B17/064 ,  A61B17/22

CPC classification number: A61F2/2436 ,  A61B17/0401 ,  A61F2/2409 ,  A61F2/2418 ,  A61F2/2454 ,  A61F2/2457 ,  A61B2017/0409 ,  A61B2017/0441 ,  A61B2017/0649 ,  A61B2017/22068 ,  A61F2220/0008 ,  A61F2250/0003

Abstract: The disclosure provides systems and related methods for delivering a prosthesis to a target location. The system includes a tether delivery catheter and a prosthesis delivery catheter, and also can include a lock delivery catheter or knot pusher, as desired. Various embodiments of useful valve prostheses are also disclosed.

公开(公告)号：US20240341953A1

公开(公告)日：2024-10-17

申请号：US18612625

申请日：2024-03-21

Applicant: St. Jude Medical, Cardiology Division, Inc.

Inventor： Theodore Paul Dale ,  Katherine A. Ahmann ,  Brian Joseph Perszyk ,  Mathias Charles Glimsdale ,  Kristopher Henry Vietmeier

IPC: A61F2/24

CPC classification number: A61F2/2418 ,  A61F2/2412 ,  A61F2210/0014 ,  A61F2220/0008 ,  A61F2250/006

Abstract: A prosthetic heart valve includes a collapsible and expandable stent extending along a longitudinal axis and having an inflow end and an outflow end, the stent including a plurality of cells annularly arranged around the stent in at least one row, the plurality of cells having a first nesting cell adjacent the outflow end of the stent, a first engaging arm disposed within the first nesting cell and being pivotally movable between a loaded condition, a partially-released condition, and a fully-released condition, the first engaging arm and the first nesting cell having a synchronous pivoting movement, and a collapsible and expandable valve assembly disposed within the stent and having a plurality of leaflets.

公开(公告)号：US12115066B2

公开(公告)日：2024-10-15

申请号：US18370740

申请日：2023-09-20

Applicant: EDWARDS LIFESCIENCES CORPORATION

Inventor： Izaak Rosen ,  Bich Hoang Pham ,  Timothy C. Ulrich ,  Tammy Nguyen ,  Jiangxue Han

IPC: A61F2/24

CPC classification number: A61F2/2418 ,  A61F2220/0075

Abstract: This disclosure is directed to prosthetic heart valves having elongated sealing members. As one example, a prosthetic heart valve comprises an annular frame, a leaflet assembly comprising a plurality of leaflets, and a skirt assembly comprising an inner skirt, an outer skirt, and/or a third skirt. The frame is radially compressible and expandable between a radially compressed state and a radially expanded state and comprises a plurality of apices at an inflow end. The skirt assembly forms a pocket at the inflow end of the frame that creates extra space between the inflow end of the frame and the skirt assembly when the frame is in the radially expanded state. This pocket allows the apices at the inflow end of the frame to move towards an inflow end of the pocket when the frame is radially compressed to the radially compressed state without protruding through the skirt assembly.

公开(公告)号：US12115062B2

公开(公告)日：2024-10-15

申请号：US18109075

申请日：2023-02-13

Applicant: EDWARDS LIFESCIENCES CORPORATION

Inventor： Mark Chau ,  Marlowe E. Patterson ,  Seung-Beom Yi ,  Stephen C. Geist ,  Travis Zenyo Oba

IPC: A61F2/24

CPC classification number: A61F2/2412 ,  A61F2/2409 ,  A61F2/2418 ,  A61F2/2427 ,  A61F2/2445 ,  A61F2/246 ,  A61F2210/0014 ,  A61F2220/0008 ,  A61F2220/0016 ,  A61F2230/0069 ,  A61F2250/006 ,  A61F2250/0063

Abstract: A prosthetic heart valve for implantation at a native heart valve includes a multi-part frame. The multi-part frame includes a cylindrical main body and a ventricular anchor component surrounding the main body. The main body includes a plurality of struts arranged in a lattice pattern. The ventricular anchor component is attached to the main body only at an outflow end of the main body and extends toward an inflow end of the main body. The prosthetic valve further includes a valve structure having three leaflets made from pericardium. The multi-part frame is radially compressible for delivery within a sheath of a delivery catheter and is self-expandable for deployment within an annulus of the native valve. The main body and the ventricular anchor component are formed separately and are attached by a locking mechanism for reducing strain between the main body and the ventricular anchor component.

公开(公告)号：US20240325144A1

公开(公告)日：2024-10-03

申请号：US18742979

申请日：2024-06-13

Applicant: EDWARDS LIFESCIENCES CORPORATION

Inventor： Stephen C. Geist ,  Robert C. Taft ,  Travis Zenyo Oba ,  Sam Sok ,  Matthew A. Peterson ,  Kevin M. Golemo ,  Mark Chau ,  Seung-Beom Yi

IPC: A61F2/24 ,  A61B6/00 ,  A61B8/12

CPC classification number: A61F2/2418 ,  A61F2/2409 ,  A61F2/2412 ,  A61F2/2436 ,  A61F2/2466 ,  A61B6/4441 ,  A61B8/12 ,  A61F2210/0014 ,  A61F2220/0008 ,  A61F2220/0016 ,  A61F2220/0075 ,  A61F2230/005 ,  A61F2230/0054 ,  A61F2230/0078 ,  A61F2250/0018 ,  A61F2250/0029 ,  A61F2250/0069

Abstract: A prosthetic heart valve for implantation within a native atrioventricular heart valve. The prosthetic heart valve includes a self-expanding frame having an annular main body and a valve member disposed within the main body. The prosthetic heart valve includes an atrial sealing member formed by a fabric cover and a plurality of arms that are arranged side-by-side in a circumferential direction around the main body. The atrial sealing member extends radially outwardly from the main body and a peripheral portion of the atrial sealing member curves upwardly for conforming to surrounding native anatomy. The prosthetic heart valve further includes one or more ventricular anchors extending from the main body for capturing native leaflet tissue and thereby securing the prosthetic heart valve within the native atrioventricular heart valve.