Production of fucosyl antigens and antibodies for recognizing same
determination of cancer associated carbohydrate linkage using same and
kit for the determination
    1.
    发明授权
    Production of fucosyl antigens and antibodies for recognizing same determination of cancer associated carbohydrate linkage using same and kit for the determination 失效
    生产岩藻糖基抗原和抗体,用于识别使用相同的癌症相关碳水化合物连锁的确定和用于测定的试剂盒

    公开(公告)号:US4725557A

    公开(公告)日:1988-02-16

    申请号:US573920

    申请日:1984-01-19

    摘要: The invention relates to a process for producing a fucosyl antigen charcterized in that an oligosaccharide contaning an .alpha.-fucoyransoyl-(1.fwdarw.3)-, -(1.fwdarw.4)- or -(1.fwdarw.6)-galactoyransoyl group and serving as a hapten is reacted wtih a carrier protein to obtain a carbohydrate antigen and to a process for producing from the antigen an antibody having specific reactivity with cells of cancers of the digestive system, especially human colon carcinoma cells, and murine teratocarcinoma cells.The invention also relates to a method of determining a cancer associated crabohydrate linkage with use of such antibody capable of specifically recognizing specific carbohydrate linkage and to a cancer diagnosing kit containing the antibody.

    摘要翻译: PCT No.PCT / JP83 / 00169 Sec。 371日期1984年1月19日 102(e)日期1984年1月19日PCT提交1983年5月28日PCT公布。 公开号WO83 / 04311 日期:1983年12月8日。本发明涉及一种制备岩藻糖基抗原的方法,其特征在于,含有α-羧基酰基 - (1-> 3) - , - (1-> 4) - 或 - (1- > 6) - 半乳糖基,并且作为半抗原与载体蛋白质反应以获得碳水化合物抗原,以及从抗原产生与消化系统癌症特别是人结肠癌细胞的细胞具有特异性反应性的抗体 ,和鼠类畸胎癌细胞。 本发明还涉及使用能够特异性识别特定碳水化合物连接的这种抗体以及含有该抗体的癌症诊断试剂盒来测定与癌症相关的水合物结合的方法。

    Exhaust unit support device
    2.
    发明授权
    Exhaust unit support device 失效
    排气装置支撑装置

    公开(公告)号:US4494722A

    公开(公告)日:1985-01-22

    申请号:US401910

    申请日:1982-07-26

    CPC分类号: F01N13/1822 B60K13/04

    摘要: In an exhaust system of an internal combustion engine installed on an automotive vehicle having a body structure wherein the exhaust system includes exhaust-system component units such as an exhaust pipe and an exhaust-cleaning catalytic converter, an exhaust unit support device for having the exhaust-system component units mounted on the vehicle body structure, comprising a first coupling member securely mounted on at least one of the exhaust-system component units, a second coupling member securely attached to the body structure, an elastic support member having a portion securely attached to the first coupling member and a portion securely attached to the second coupling member, and a vibration-damping block having a portion connected to the second coupling member and a portion connected to the vehicle body structure.

    摘要翻译: 在安装在具有主体结构的机动车辆的内燃机的排气系统中,排气系统包括诸如排气管和排气净化催化转化器的排气系统部件单元,排气单元支撑装置用于使排气 系统部件单元,其安装在车体结构上,包括牢固地安装在排气系统部件单元中的至少一个上的第一联接构件,牢固地附接到主体结构的第二联接构件,具有牢固地附接的部分的弹性支撑构件 连接到第一联接构件和牢固地附接到第二联接构件的部分,以及具有连接到第二联接构件的部分和连接到车身结构的部分的减振块。