公开(公告)号：US20220251463A1

公开(公告)日：2022-08-11

申请号：US17611986

申请日：2019-05-17

Applicant: Thorsten Kief ,  Horst Kief

Inventor： Thorsten Kief ,  Horst Kief

IPC: C10L1/198 ,  C10L10/02 ,  C10L1/12 ,  F02B47/02 ,  F01P3/02 ,  F02M25/03

Abstract: Method for reducing the pollutant emissions of internal combustion engines, wherein an aqueous solution containing glyoxal and a polymer product of citric acid and glycerol is added as an additive, additive for reducing the pollutant emissions of internal combustion engines, said additive consisting of an aqueous solution containing glyoxal and a polymer product of citric acid and glycerol, and the use thereof for reducing pollutant emissions.

公开(公告)号：US20110177036A1

公开(公告)日：2011-07-21

申请号：US13018216

申请日：2011-01-31

Applicant: Horst KIEF ,  Thorsten Kief

Inventor： Horst KIEF ,  Thorsten Kief

IPC: A61K35/12 ,  G01N33/53 ,  A61K35/16 ,  A61P35/00

CPC classification number: A61K35/14 ,  A61K39/02 ,  A61K2039/5158 ,  C12N5/0634 ,  C12N2500/38

Abstract: The present invention relates to a whole-blood culture containing specific immunocompetent killer cells that are activated against tumor cells, viruses, bacteria and/or allergens, whereby the whole-blood culture consists of whole-blood and a culture medium at a ratio of 3:1 to 4:1, whereby the culture medium has an oxygen excess of at least 100% or more and contains a water-soluble emulsification product comprising a mixture of phospholipids, vitamin E, and low-molecular proteoglycans with a molecular weight of 1,200 to 12,000 Dalton, and whereby dead tumor cells or fragments thereof and/or viral and/or bacterial antigens and/or allergens have been added to the whole-blood culture [to serve] as antigen in the specific recognition process for production of the activated killer cells (stimulation). The invention also relates to a method for producing the culture, as well as stimulants for the whole-blood culture and a method for the selection thereof.

Abstract translation: 本发明涉及一种含有针对肿瘤细胞，病毒，细菌和/或过敏原活化的特异性免疫活性杀伤细胞的全血培养物，其中全血培养物以3％的比例由全血和培养基组成 ：1〜4：1，由此培养基的氧过量至少为100％以上，并且含有水分子性乳化产物，其包含分子量为1,200的磷脂，维生素E和低分子蛋白聚糖的混合物 至12,000道尔顿，并且由此将死亡肿瘤细胞或其片段和/或病毒和/或细菌抗原和/或过敏原加入到用于生产活化的特定识别过程中的全血培养物（作为）作为抗原 杀伤细胞（刺激）。 本发明还涉及一种生产该培养物的方法以及用于全血培养的兴奋剂及其选择方法。