Mesoporous materials and methods of making the same
    1.
    发明授权
    Mesoporous materials and methods of making the same 失效
    介孔材料和制作方法

    公开(公告)号:US06696258B1

    公开(公告)日:2004-02-24

    申请号:US09598717

    申请日:2000-06-21

    IPC分类号: G01N3353

    CPC分类号: C01B37/02 A61K9/143

    摘要: Mesoporous materials and a method for making such materials is disclosed in which the mesoporous materials are made by forming an aqueous solution having an organometallic compound; adding a solution comprising a pore forming material selected from the group consisting of monomeric polyols, polyacids, polyamines, carbohydrates, oligopeptides, oligonucleic acids, carbonyl functional organic compounds, and mixtures and derivatives of these materials to form a sol get matrix by polycondensation; drying the sot gel matrix; and removing the pore forming material from the dried sot-gel matrix to thereby form a mesoporous material. The mesoporous materials have pore diameters of from about 20 Å to about 100 Å and may be used with a biologically active agent immobilized within the pores of the mesoporous material and introduced into a biological system.

    摘要翻译: 公开了介孔材料和制造这种材料的方法,其中介孔材料是通过形成具有有机金属化合物的水溶液制成的; 添加包含选自单体多元醇,多元酸,多胺,碳水化合物,寡肽,低聚核酸,羰基官能化有机化合物的成孔材料的溶液和这些材料的混合物和衍生物,以通过缩聚形成溶胶获得基质; 干燥sot凝胶基质; 并从干燥的胶原基质中除去成孔材料,从而形成介孔材料。 介孔材料的孔径为约从至约于100埃,并且可以与固定在介孔材料的孔内的生物活性剂一起使用并被引入到生物系统中。