公开(公告)号：US08104348B2

公开(公告)日：2012-01-31

申请号：US11921624

申请日：2006-04-15

Applicant: Klaus Balschat ,  Tobias Fritsche ,  Alfred Gagel ,  Steffen Kirchner ,  Hans-Joachim Muench ,  Olaf Nicholas ,  Jochen Schneider ,  Reiner Spickermann ,  Santer Zur Host-Meyer

Inventor： Klaus Balschat ,  Tobias Fritsche ,  Alfred Gagel ,  Steffen Kirchner ,  Hans-Joachim Muench ,  Olaf Nicholas ,  Jochen Schneider ,  Reiner Spickermann ,  Santer Zur Host-Meyer

IPC: G01H3/12

CPC classification number: G01N29/032 ,  A61M1/3626 ,  G01N2291/02433 ,  G01N2291/02466 ,  G01N2291/02854

Abstract: The present invention relates to a method and a device for monitoring a flowing medium, in particular the blood flowing in an extracorporeal blood circulation, for the presence of air, in particular micro-bubbles. A sequence of signal pulses or a continuous signal is injected into the flowing medium, and the signal pulses or continuous signal leaving the flowing medium are received. To detect micro-bubbles, a signal pattern that is characteristic of the variation over time of the received signal pulses or the continuous signal in a predetermined period of time is extracted from the signal received. The characteristic signal pattern is compared with one or more characteristic reference patterns, and the presence of air bubbles is determined if the characteristic signal pattern deviates from the characteristic reference pattern by a predetermined amount. Statistical characteristic variables, in particular the variance, are preferably determined from the signal patterns and compared with one another.

Abstract translation: 本发明涉及用于监测流动介质，特别是在体外血液循环中流动的血液，用于存在空气，特别是微气泡的方法和装置。 信号脉冲序列或连续信号被注入到流动介质中，并且接收离开流动介质的信号脉冲或连续信号。 为了检测微气泡，从接收到的信号中提取出在接收到的信号脉冲或连续信号随时间变化的特征的信号模式。 将特征信号图案与一个或多个特征参考图案进行比较，并且如果特征信号图案偏离特征参考图案预定量，则确定气泡的存在。 统计特征变量，特别是方差，优选地根据信号图案确定并相互比较。

公开(公告)号：US20090205426A1

公开(公告)日：2009-08-20

申请号：US11921624

申请日：2006-04-15

Applicant: Klaus Balschat ,  Tobias Fritsche ,  Alfred Gagel ,  Steffen Kirchner ,  Hans-Joachim Muench ,  Olaf Nicholas ,  Jochen Schneider ,  Reiner Spickermann ,  Santer Zur Host-Meyer

Inventor： Klaus Balschat ,  Tobias Fritsche ,  Alfred Gagel ,  Steffen Kirchner ,  Hans-Joachim Muench ,  Olaf Nicholas ,  Jochen Schneider ,  Reiner Spickermann ,  Santer Zur Host-Meyer

IPC: G01N29/032

CPC classification number: G01N29/032 ,  A61M1/3626 ,  G01N2291/02433 ,  G01N2291/02466 ,  G01N2291/02854

Abstract: The present invention relates to a method and a device for monitoring a flowing medium, in particular the blood flowing in an extracorporeal blood circulation, for the presence of air, in particular micro-bubbles. A sequence of signal pulses or a continuous signal is injected into the flowing medium, and the signal pulses or continuous signal leaving the flowing medium are received. To detect micro-bubbles, a signal pattern that is characteristic of the variation over time of the received signal pulses or the continuous signal in a predetermined period of time is extracted from the signal received. The characteristic signal pattern is compared with one or more characteristic reference patterns, and the presence of air bubbles is determined if the characteristic signal pattern deviates from the characteristic reference pattern by a predetermined amount. Statistical characteristic variables, in particular the variance, are preferably determined from the signal patterns and compared with one another.

Abstract translation: 本发明涉及用于监测流动介质，特别是在体外血液循环中流动的血液，用于存在空气，特别是微气泡的方法和装置。 信号脉冲序列或连续信号被注入到流动介质中，并且接收离开流动介质的信号脉冲或连续信号。 为了检测微气泡，从接收到的信号中提取出在接收到的信号脉冲或连续信号随时间变化的特征的信号模式。 将特征信号图案与一个或多个特征参考图案进行比较，并且如果特征信号图案偏离特征参考图案预定量，则确定气泡的存在。 统计特征变量，特别是方差，优选地根据信号图案确定并相互比较。

公开(公告)号：US09016137B2

公开(公告)日：2015-04-28

申请号：US13472404

申请日：2012-05-15

Applicant: Hans-Joachim Muench ,  Santer zur Horst-Meyer ,  Tobias Fritsche ,  Jürgen Kahle ,  Werner Krause ,  Nicki Bader

Inventor： Hans-Joachim Muench ,  Santer zur Horst-Meyer ,  Tobias Fritsche ,  Jürgen Kahle ,  Werner Krause ,  Nicki Bader

IPC: G01F1/66

CPC classification number: G01F1/667

Abstract: For flow measurement a device with a compact housing and a fixable hinged cover has a measuring channel for inserting a flexible tube such that it becomes deformed in a defined way. The measuring channel extends over the entire width of the housing. A measuring cell arranged in the center of the measuring channel has four ceramics I, II, III, IV, integrated in a sound-decoupled way and facing each other diagonally in pairs, which are placed in lateral parts on the left and on the right of the measuring cell, and a base plate limiting the measuring cell downwards in the direction of an installation space for an electric evaluation system, wherein the base plate also limits the remaining area of the measuring channel from below.

Abstract translation: 对于流量测量，具有紧凑壳体和可固定铰链盖的装置具有用于插入柔性管的测量通道，使得其以限定的方式变形。 测量通道在壳体的整个宽度上延伸。 设置在测量通道中心的测量单元具有四个陶瓷I，II，III，IV，它们以声音解耦的方式成对地对置并且彼此成对地对置，它们被放置在左侧和右侧的侧向部分 的测量单元，以及基板，用于在电气评估系统的安装空间的方向上向下限制测量单元，其中，基板还从下方限制测量通道的剩余面积。

公开(公告)号：US20130305839A1

公开(公告)日：2013-11-21

申请号：US13472404

申请日：2012-05-15

Applicant: Hans-Joachim Muench ,  Santer zur Horst-Meyer ,  Tobias Fritsche ,  Jürgen Kahle ,  Werner Krause ,  Nicki Bader

Inventor： Hans-Joachim Muench ,  Santer zur Horst-Meyer ,  Tobias Fritsche ,  Jürgen Kahle ,  Werner Krause ,  Nicki Bader

IPC: G01F1/05

CPC classification number: G01F1/667

Abstract: The invention relates to a device for the contactless flow measurement of fluids in flexible tubes.

Abstract translation: 本发明涉及一种用于柔性管中流体的非接触式流量测量的装置。