公开(公告)号：US20100047313A1

公开(公告)日：2010-02-25

申请号：US12544577

申请日：2009-08-20

Applicant: Tom PRIEBE ,  Umang ANAND ,  Lance GIBSON ,  Les CLAPP ,  Michael KUEHLING

Inventor： Tom PRIEBE ,  Umang ANAND ,  Lance GIBSON ,  Les CLAPP ,  Michael KUEHLING

IPC: A61F2/04 ,  A61K31/337 ,  A61P7/00

CPC classification number: A61L27/34 ,  A61L27/50 ,  A61L27/54 ,  A61L31/10 ,  A61L31/14 ,  A61L31/16 ,  A61L2300/606 ,  C08L101/12

Abstract: Medical devices having a coating comprising an ionic polymer for electromagnetically-controlled release of a therapeutic agent. Release of the therapeutic agent from the coating is facilitated or modulated by the application of an electromagnetic field to the medical device. Exposure to the electromagnetic field may cause the release of the therapeutic agent in various ways, including electrochemical changes in the ionic polymer, structural changes in the coating and/or ionic polymers, changes in the permeability of the coating, changes in the orientation of the ionic polymers, or motion of the ionic polymers. Also disclosed are methods for delivering a therapeutic agent using electromagnetic fields.

Abstract translation: 具有包含用于电磁控制释放治疗剂的离子聚合物的涂层的医疗装置。 通过向医疗装置施加电磁场来促进或调节治疗剂从涂层的释放。 暴露于电磁场可能导致治疗剂以各种方式释放，包括离子聚合物的电化学变化，涂层和/或离子聚合物的结构变化，涂层渗透性的变化， 离子聚合物或离子聚合物的运动。 还公开了使用电磁场递送治疗剂的方法。