公开(公告)号：US20110172445A1

公开(公告)日：2011-07-14

申请号：US13001676

申请日：2009-06-26

申请人： Yusuke Wataya ,  Hye-Sook Kim ,  Akiko Hiramoto ,  Akira Sato ,  Nobuo Ota ,  Takashi Kumagai ,  Rieko Shimogawara ,  Toshie Taniguchi

发明人： Yusuke Wataya ,  Hye-Sook Kim ,  Akiko Hiramoto ,  Akira Sato ,  Nobuo Ota ,  Takashi Kumagai ,  Rieko Shimogawara ,  Toshie Taniguchi

IPC分类号： C07D323/00

CPC分类号： C07D323/00 ,  A61K31/357 ,  C07D325/00 ,  Y02A50/423

摘要： An object of the present invention is to provide a novel antischistosomal agent, and more specifically, to provide a novel drug capable of inhibiting a growth of schistosomes in vivo to prevent development of liver dysfunction due to eggs of the schistosomes in the case of infection with the schistosomes. The novel antischistosomal agent includes as an active ingredient a peroxide derivative. Specifically, the novel antischistosomal agent includes as an active ingredient a peroxide derivative represented by the general formula (I): where C represents an alicyclic hydrocarbon ring group which may be substituted, and n represents an integer of 1 to 6.

摘要翻译： 本发明的目的是提供一种新的抗血吸虫药，更具体地说，提供一种能够在体内抑制血吸虫生长的新型药物，以防止在感染情况下由于血吸虫卵产生的肝功能障碍的发展 血吸虫 新型抗血吸虫药包括作为活性成分的过氧化物衍生物。 具体地说，新型抗血吸虫药包括作为活性成分的通式（I）表示的过氧化物衍生物：其中C表示可被取代的脂环族烃环基，n表示1〜6的整数。