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公开(公告)号:US07276602B2
公开(公告)日:2007-10-02
申请号:US10626406
申请日:2003-07-24
IPC分类号: C07D412/02 , C07D417/12
CPC分类号: C07D417/12
摘要: The invention relates to compounds of the formula 1 or pharmaceutically acceptable salts, prodrugs, solvates or hydrates thereof, wherein wherein X, R1, and R2 are as defined herein. The invention also relates to pharmaceutical compositions containing the compounds of formula 1 and to methods of treating hyperproliferative disorders in a mammal by administering the compounds of formula 1.
摘要翻译: 本发明涉及式1的化合物或其药学上可接受的盐,前药,溶剂化物或水合物,其中X,R 1和R 2如本文所定义。 本发明还涉及含有式1化合物的药物组合物和通过施用式1化合物治疗哺乳动物中过度增殖性疾病的方法。