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公开(公告)号：US20160287620A1
公开(公告)日：2016-10-06
申请号：US15023470
申请日：2014-09-22
发明人： Francois MORVAN , Jean-Jacques VASSEUR , Caroline LIGEOUR , Yann CHEVOLOT , Eliane SOUTEYRAND , Olivier VIDAL , Alice GOUDOT , Sebastien VIDAL
IPC分类号： A61K31/7056 , A61K9/00 , C07H15/26 , A61K45/06
CPC分类号： A61K31/7056 , A61K9/0073 , A61K31/70 , A61K31/7052 , A61K45/06 , C07H15/26 , A61K2300/00
摘要： A molecule responding to formula (I)of the glycocluster type with galactose residues at their extremities. Simple and efficient methods for the preparation of these compounds. Medical use of compounds (I) as inhibitors of infections by Pseudomonas aeruginosa, more specifically as inhibitors of Pseudomonas aeruginosa's virulence.
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2.发明申请SUGAR-ANALOG PHOSPHORUS-CONTAINING HETEROCYCLES HAVING AN ANTI-METASTATIC ACTIVITY 审中-公开具有抗细胞活性的含糖类含磷的杂环化合物公开(公告)号：US20150376216A1
公开(公告)日：2015-12-31
申请号：US14769928
申请日：2014-02-25
申请人： CENTRE NATIONAL DE LA RECHERCHE SCIENTIRIQUE , ECOLE NATIONALE SUPERIEURE DE CHIMIE DE MONTPELLIE , UNIVERSITE MONTPELLIER 1 , UNIVERSITE MONTPELLIER 2 SCIENCES ET TECHNIQUES , UNIVERSITE PARIS-NORD 13 , UNIVERSITE PARIS-SUD 11
发明人： Norbert BAKALARA , Marcel DELAFORGE , Marc LECOUVEY , Jean-Philippe HUGNOT , Philippe LEGRAND , Jean-Luc PIRAT , David VIRIEUX , Jean-Noel VOLLE
IPC分类号： C07F9/6571 , A61K45/06 , A61K31/665
CPC分类号： C07F9/657172 , A61K9/0019 , A61K9/08 , A61K31/665 , A61K31/67 , A61K31/675 , A61K45/06 , A61K47/14 , C07D493/04 , C07F9/6552 , C07F9/65522 , A61K2300/00
摘要： The use of compounds of formula (1) as defined in the description, for reducing or preventing the onset of metastases in a patient suffering from cancer. Pharmaceutical compositions for using in human or veterinary medicine, including at least one compound of formula (1) are also described.
摘要翻译： 使用描述中定义的式（1）化合物，用于减少或预防患有癌症的患者的转移发生。 还描述了用于人或兽医学包括至少一种式（1）化合物的药物组合物。
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公开(公告)号：US10179816B2
公开(公告)日：2019-01-15
申请号：US15333519
申请日：2016-10-25
申请人： LABORATOIRE FRANCAIS DU FRACTIONNEMENT DES BIOTECHNOLOGIES , CENTRE REGIONAL DE LUTTE CONTRE LE CANCER , I.N.S.E.R.M. (INSTITUT NATIONAL DE LA SANTÉ ET DE LA RECHERCHE MÉDICALE) , UNIVERSITE MONTPELLIER 1
IPC分类号： A61K39/395 , C07K16/28 , A61K31/282 , A61K31/337 , A61K45/06 , A61K33/24 , A61K9/00 , C07K16/30 , A61K39/00
摘要： The invention relates to novel pharmaceutical compositions including, as active ingredient, an antibody binding the human anti-Müllerian hormone type II receptor (AMHR-II) and an anticancer agent, as well as the therapeutic applications of these compositions.
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公开(公告)号：US20160032329A1
公开(公告)日：2016-02-04
申请号：US14884831
申请日：2015-10-16
摘要： The present invention relates to composition and methods of producing bioenergy. More specifically, the invention relates to the use of bacterium of the genus Deinococcus and/or related genera for the modification of biomass or biomass derivatives with a view to producing bioenergy products and metabolites.
摘要翻译： 本发明涉及生物能源生产的组合物和方法。 更具体地，本发明涉及用于生物质或生物质衍生物的改性的用于产生生物能源产物和代谢物的用于脱肠球菌属和/或相关属的细菌的用途。
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5.发明授权Pharmaceutical compositions comprising an antibody which binds the human anti-mullerian hormone receptor type II 有权药物组合物，其包含结合人类抗髓激素受体II型的抗体公开(公告)号：US09511138B2
公开(公告)日：2016-12-06
申请号：US14367969
申请日：2012-12-21
申请人： LFB BIOTECHNOLOGIES , CENTRE NATIONAL DE LUTTE CONTRE LE CANCER , I.N.S.E.R.M. (INSTITUT NATIONAL DE LA SANTÉ ET DE LA RECHERCHE MÉDICALE , UNIVERSITE MONTPELLIER 1
IPC分类号： A61K39/395 , A61K31/337 , A61K31/282 , C07K16/28 , A61K45/06 , A61K33/24
CPC分类号： C07K16/2869 , A61K9/0019 , A61K31/282 , A61K31/337 , A61K33/24 , A61K39/39533 , A61K39/3955 , A61K39/39558 , A61K45/06 , A61K2039/505 , C07K16/28 , C07K16/3069 , C07K2317/24 , C07K2317/92 , A61K2300/00
摘要： The invention relates to novel pharmaceutical compositions including, as active ingredient, an antibody binding the human anti-Müllerian hormone type II receptor (AMHR-II) and an anticancer agent, as well as the therapeutic applications of these compositions.
摘要翻译： 本发明涉及包含作为活性成分的结合人类抗Müllerian激素II型受体（AMHR-II）和抗癌剂的新型药物组合物，以及这些组合物的治疗应用。
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6.发明申请公开(公告)号：US20170101478A1
公开(公告)日：2017-04-13
申请号：US15333519
申请日：2016-10-25
申请人： LABORATOIRE FRANCAIS DU FRACTIONNEMENT DES BIOTECHNOLOGIES , CENTRE REGIONAL DE LUTTE CONTRE LE CANCER , I.N.S.E.R.M. (INSTITUT NATIONAL DE LA SANTÉ ET DE LA RECHERCHE MÉDICALE) , UNIVERSITE MONTPELLIER 1
IPC分类号： C07K16/28 , C07K16/30 , A61K39/395 , A61K9/00 , A61K31/282 , A61K31/337
CPC分类号： C07K16/2869 , A61K9/0019 , A61K31/282 , A61K31/337 , A61K33/24 , A61K39/39533 , A61K39/3955 , A61K39/39558 , A61K45/06 , A61K2039/505 , C07K16/28 , C07K16/3069 , C07K2317/24 , C07K2317/92 , A61K2300/00
摘要： The invention relates to novel pharmaceutical compositions including, as active ingredient, an antibody binding the human anti-Müllerian hormone type II receptor (AMHR-II) and an anticancer agent, as well as the therapeutic applications of these compositions.
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7.发明申请公开(公告)号：US20140342936A1
公开(公告)日：2014-11-20
申请号：US14364331
申请日：2012-12-17
申请人： INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE) , UNIVERSITE MONTPELLIER 1 , CENTRE HOSPITALIER UNIVERSITAIRE DE MONTPELLIER
IPC分类号： G01N33/569
摘要： The present invention relates to a method for diagnosing latent tuberculosis infection in a subject comprising the step i) consisting of incubating a biological sample obtained from the subject with at least one Mycobacterium tuberculosis antigen, and thereafter a step ii) consisting of quantifying in said biological sample the secretion of at least one cytokine selected from the group consisting of IL-2, IL-15, IP-10 and MIG.
摘要翻译： 本发明涉及一种用于诊断受试者潜在结核感染的方法，包括步骤i），其包括将从受试者获得的生物样品与至少一种结核分枝杆菌抗原一起孵育，然后将由所述生物学定量的步骤ii） 对从IL-2，IL-15，IP-10和MIG组成的组中选择的至少一种细胞因子的分泌进行采样。
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