公开(公告)号：US20110028518A1

公开(公告)日：2011-02-03

申请号：US12921873

申请日：2009-03-18

Applicant: Naveen Kumar Kolla ,  Nagaraju Manne ,  Srinivas Gangula ,  Udaykumar Neelam ,  Anitha Naredla ,  Sudhakar Reddy Baddam ,  Sumeet Vishwasrao Patil ,  Arjunkumar Tummala ,  Subbareddy Peddireddy ,  Sachin Gulabrao Shinde ,  Ashok Sigala ,  Satish Varma Mudunuru ,  Madhu Kiran Tummidi

Inventor： Naveen Kumar Kolla ,  Nagaraju Manne ,  Srinivas Gangula ,  Udaykumar Neelam ,  Anitha Naredla ,  Sudhakar Reddy Baddam ,  Sumeet Vishwasrao Patil ,  Arjunkumar Tummala ,  Subbareddy Peddireddy ,  Sachin Gulabrao Shinde ,  Ashok Sigala ,  Satish Varma Mudunuru ,  Madhu Kiran Tummidi

IPC: A61K31/4439 ,  C07D401/12 ,  A61P1/04

CPC classification number: C07D401/12 ,  A61K9/1635 ,  A61K9/1652 ,  A61K47/6951 ,  B82Y5/00

Abstract: Processes for the preparation of dexlansoprazole, an amorphous form of dexlansoprazole, a solid dispersion of amorphous dexlansoprazole and a pharmaceutically acceptable carrier, and processes for their preparation. Also provided are crystalline compounds 2-[(R)-[(4-chloro-3-methyl-2-pyridinyl)methyl]sulfinyl]-1H-benzimidazole and 2-[(R)-[(4-nitro-3-methyl-2-pyridinyl)methyl]sulfinyl]-1H-benzimidazole, and methods for their preparation.

Abstract translation: 右兰索拉唑，无效形式的右兰索拉唑，无定形右兰索拉唑的固体分散体和药学上可接受的载体的方法及其制备方法。 还提供了结晶化合物2 - [（R） - [（4-氯-3-甲基-2-吡啶基）甲基]亚磺酰基] -1H-苯并咪唑和2 - [（R） - [（4-硝基-3- 甲基-2-吡啶基）甲基]亚磺酰基] -1H-苯并咪唑及其制备方法。

公开(公告)号：US20090263475A1

公开(公告)日：2009-10-22

申请号：US12426537

申请日：2009-04-20

Applicant: Nagaraju Manne ,  Udaykumar Neelam ,  Sudhakar Reddy Baddam ,  Naveen Kumar Kolla ,  Venkata Nookaraju Sreedharala ,  Chandra Sekhar Veera Venkata Naga Bulusu

Inventor： Nagaraju Manne ,  Udaykumar Neelam ,  Sudhakar Reddy Baddam ,  Naveen Kumar Kolla ,  Venkata Nookaraju Sreedharala ,  Chandra Sekhar Veera Venkata Naga Bulusu

IPC: A61K9/48 ,  A61K9/24 ,  A61K9/28 ,  A61K9/14 ,  A61K31/4439

CPC classification number: A61K31/4439 ,  A61K9/145 ,  A61K9/1611 ,  A61K9/1623 ,  A61K9/1635 ,  A61K9/1652 ,  A61K9/2018 ,  A61K9/4808 ,  A61K9/5026 ,  A61K9/5078 ,  A61K9/5084

Abstract: Premixes of dexlansoprazole with pharmaceutical excipients, processes for preparing premixes, pharmaceutical formulations containing the premixes, and their use in treatment of erosive esophagitis and heartburn associated with non-erosive gastroesophageal reflux disease.

Abstract translation: 右旋兰索拉与药物赋形剂的预混合物，制备预混合物的方法，含有该预混物的药物制剂及其在治疗侵蚀性食道炎和与非侵蚀性胃食管反流病相关的胃灼热中的应用。

公开(公告)号：US20120231073A1

公开(公告)日：2012-09-13

申请号：US13475565

申请日：2012-05-18

Applicant: Nagaraju Manne ,  Udaykumar Neelam ,  Sudhakar Reddy Baddam ,  Naveen Kumar Kolla ,  Venkata Nookaraju Sreedharala ,  Chandra Sekhar Veera Venkata Naga Bulusu

Inventor： Nagaraju Manne ,  Udaykumar Neelam ,  Sudhakar Reddy Baddam ,  Naveen Kumar Kolla ,  Venkata Nookaraju Sreedharala ,  Chandra Sekhar Veera Venkata Naga Bulusu

IPC: A61K31/4439 ,  A61P1/04 ,  A61K9/52 ,  A61K9/14 ,  A61K9/48

CPC classification number: A61K31/4439 ,  A61K9/145 ,  A61K9/1611 ,  A61K9/1623 ,  A61K9/1635 ,  A61K9/1652 ,  A61K9/2018 ,  A61K9/4808 ,  A61K9/5026 ,  A61K9/5078 ,  A61K9/5084

Abstract: Premixes of dexlansoprazole with pharmaceutical excipients, processes for preparing premixes, pharmaceutical formulations containing the premixes, and their use in treatment of erosive esophagitis and heartburn associated with non-erosive gastroesophageal reflux disease.

Abstract translation: 右旋兰索拉与药物赋形剂的预混合物，制备预混物的方法，含有该预混合物的药物制剂及其在治疗侵蚀性食管炎和与非侵蚀性胃食管反流病相关的胃灼热中的应用。