公开(公告)号：US20110028518A1

公开(公告)日：2011-02-03

申请号：US12921873

申请日：2009-03-18

Applicant: Naveen Kumar Kolla ,  Nagaraju Manne ,  Srinivas Gangula ,  Udaykumar Neelam ,  Anitha Naredla ,  Sudhakar Reddy Baddam ,  Sumeet Vishwasrao Patil ,  Arjunkumar Tummala ,  Subbareddy Peddireddy ,  Sachin Gulabrao Shinde ,  Ashok Sigala ,  Satish Varma Mudunuru ,  Madhu Kiran Tummidi

Inventor： Naveen Kumar Kolla ,  Nagaraju Manne ,  Srinivas Gangula ,  Udaykumar Neelam ,  Anitha Naredla ,  Sudhakar Reddy Baddam ,  Sumeet Vishwasrao Patil ,  Arjunkumar Tummala ,  Subbareddy Peddireddy ,  Sachin Gulabrao Shinde ,  Ashok Sigala ,  Satish Varma Mudunuru ,  Madhu Kiran Tummidi

IPC: A61K31/4439 ,  C07D401/12 ,  A61P1/04

CPC classification number: C07D401/12 ,  A61K9/1635 ,  A61K9/1652 ,  A61K47/6951 ,  B82Y5/00

Abstract: Processes for the preparation of dexlansoprazole, an amorphous form of dexlansoprazole, a solid dispersion of amorphous dexlansoprazole and a pharmaceutically acceptable carrier, and processes for their preparation. Also provided are crystalline compounds 2-[(R)-[(4-chloro-3-methyl-2-pyridinyl)methyl]sulfinyl]-1H-benzimidazole and 2-[(R)-[(4-nitro-3-methyl-2-pyridinyl)methyl]sulfinyl]-1H-benzimidazole, and methods for their preparation.

Abstract translation: 右兰索拉唑，无效形式的右兰索拉唑，无定形右兰索拉唑的固体分散体和药学上可接受的载体的方法及其制备方法。 还提供了结晶化合物2 - [（R） - [（4-氯-3-甲基-2-吡啶基）甲基]亚磺酰基] -1H-苯并咪唑和2 - [（R） - [（4-硝基-3- 甲基-2-吡啶基）甲基]亚磺酰基] -1H-苯并咪唑及其制备方法。

公开(公告)号：US20100210719A1

公开(公告)日：2010-08-19

申请号：US12668685

申请日：2008-07-10

Applicant: Surya Narayana Devarakonda ,  Sesha Reddy Yarraguntla ,  Venu Nalivela ,  Ram Thaimattam ,  Subbareddy Peddireddy ,  Balaji Raghupati ,  Mohammed Azeezulla Baig ,  Srinivas Reddy Gade ,  Srinivas Reddy Mallepalli ,  Vijaywardhan Chitta ,  Satyanarayana Bollikonda ,  Saravanan Mohanarangam ,  Rajasekhar Kadaboina

Inventor： Surya Narayana Devarakonda ,  Sesha Reddy Yarraguntla ,  Venu Nalivela ,  Ram Thaimattam ,  Subbareddy Peddireddy ,  Balaji Raghupati ,  Mohammed Azeezulla Baig ,  Srinivas Reddy Gade ,  Srinivas Reddy Mallepalli ,  Vijaywardhan Chitta ,  Satyanarayana Bollikonda ,  Saravanan Mohanarangam ,  Rajasekhar Kadaboina

IPC: A61K31/277 ,  A61K31/137 ,  C07C255/37 ,  C07C215/42 ,  C07C209/48 ,  C07C209/84 ,  C07C213/00 ,  A61P25/24

CPC classification number: A61K31/135 ,  A61K9/146

Abstract: Processes for preparing desvenlafaxine and stable amorphous O-desmethylvenlafaxine succinate solid dispersions with one or more pharmaceutically acceptable carriers.

Abstract translation: 用一种或多种药学上可接受的载体制备Desvenlafaxine和稳定的无定形O-去甲基文拉法辛琥珀酸酯固体分散体的方法。

公开(公告)号：US20100036164A1

公开(公告)日：2010-02-11

申请号：US12535789

申请日：2009-08-05

Applicant: Srinivas Areveli ,  Radha Krishna Singamsetty ,  Satish Kumar Vujjni ,  Vijaya Kumar Adla ,  Sreenadha Charyulu Kandala ,  Ganesh Varanasi ,  Subbareddy Peddireddy ,  Mohammed Azeezulla Baig

Inventor： Srinivas Areveli ,  Radha Krishna Singamsetty ,  Satish Kumar Vujjni ,  Vijaya Kumar Adla ,  Sreenadha Charyulu Kandala ,  Ganesh Varanasi ,  Subbareddy Peddireddy ,  Mohammed Azeezulla Baig

IPC: C07C231/00

CPC classification number: C07C315/06 ,  C07B2200/13 ,  C07C317/44

Abstract: Preparation of armodafinil crystalline Form I. Also provided is armodafinil having about 30% or more by weight of particles with sizes greater than about 250 μm, and about 70% or less by weight of particles having sizes less than about 250 μm, wherein of the particles having sizes less than about 250 μm, about 50% of them have diameters less than about 50 μm.

Abstract translation: 臂状杆菌结晶形式I的制备。还提供了具有约30重量％或更多重量的尺寸大于约250μm的颗粒和约70重量％或更少的尺寸小于约250μm的颗粒的臂多巴尼，其中 尺寸小于约250μm的颗粒，其中约50％具有小于约50μm的直径。

公开(公告)号：US20110196154A1

公开(公告)日：2011-08-11

申请号：US13042867

申请日：2011-03-08

Applicant: Rajasekhar Kadaboina ,  Sekhar Munaswamy Nariyam ,  Srividya Ramakrishnan ,  Subbareddy Peddireddy ,  Mohammed Azeezulla Baig ,  Nagakiran Duggirala

Inventor： Rajasekhar Kadaboina ,  Sekhar Munaswamy Nariyam ,  Srividya Ramakrishnan ,  Subbareddy Peddireddy ,  Mohammed Azeezulla Baig ,  Nagakiran Duggirala

IPC: C07D487/04

CPC classification number: C07D487/04

Abstract: Processes for the preparation of amorphous pemetrexed disodium, and removal of residual solvents from amorphous pemetrexed disodium.

Abstract translation: 制备无定形培美曲塞二钠的方法，并从无定形培美曲塞二钠中除去残留溶剂。

公开(公告)号：US08217039B2

公开(公告)日：2012-07-10

申请号：US12294986

申请日：2007-03-29

Applicant: Vijayavitthal Thippannachar Mathad ,  Pravinchandra Jayantilal Vankawala ,  Raviram Chandrasekhar Elati ,  Prabhakar Macharla ,  Srinivas Gangula ,  Naveen Kumar Kolla ,  Ravi Kumar Komareddy ,  Surya Narayana Devarkonda ,  Subbareddy Peddireddy

Inventor： Vijayavitthal Thippannachar Mathad ,  Pravinchandra Jayantilal Vankawala ,  Raviram Chandrasekhar Elati ,  Prabhakar Macharla ,  Srinivas Gangula ,  Naveen Kumar Kolla ,  Ravi Kumar Komareddy ,  Surya Narayana Devarkonda ,  Subbareddy Peddireddy

IPC: A61K31/53 ,  C07D417/06

CPC classification number: C07D413/06

Abstract: Intimate mixtures of aprepitant crystalline Form I and crystalline Form II, having specific weight ratios of the forms.

Abstract translation: 形式I和结晶形式II的紧密混合物，具有比例的形式。

公开(公告)号：US20100298327A1

公开(公告)日：2010-11-25

申请号：US12294986

申请日：2007-03-29

Applicant: Vijayavitthal Thippannachar Mathad ,  Pravinchandra Jayantilal Vankawala ,  Raviram Chandrasekhar Elati ,  Prabhakar Macharla ,  Srinivas Gangula ,  Naveen Kumar Kolla ,  Ravi Kumar Komareddy ,  Surya Narayana Devarkonda ,  Subbareddy Peddireddy

Inventor： Vijayavitthal Thippannachar Mathad ,  Pravinchandra Jayantilal Vankawala ,  Raviram Chandrasekhar Elati ,  Prabhakar Macharla ,  Srinivas Gangula ,  Naveen Kumar Kolla ,  Ravi Kumar Komareddy ,  Surya Narayana Devarkonda ,  Subbareddy Peddireddy

IPC: A61K31/5377 ,  C07D413/06 ,  A61P1/08

CPC classification number: C07D413/06

Abstract: Intimate mixtures of aprepitant crystalline Form I and crystalline Form II, having specific Hweight ratios of the forms.

Abstract translation: 形式I和结晶形式II的紧密混合物，其形式具有特定的重量比。