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公开(公告)号：US08138372B2
公开(公告)日：2012-03-20
申请号：US12138097
申请日：2008-06-12
IPC分类号： C07C229/04 , A61K31/205
CPC分类号： C07C235/10 , C07C233/36 , C07C271/02
摘要： The present invention covers zwitterionic, non-surface-active compounds in the form of carboxymethylated, short-chain dialkylaminoalkylamides and use thereof as therapeutic agent.
摘要翻译： 本发明涵盖羧甲基化短链二烷基氨基烷基酰胺形式的两性离子，非表面活性化合物及其作为治疗剂的用途。
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公开(公告)号：US20090054521A1
公开(公告)日：2009-02-26
申请号：US12138097
申请日：2008-06-12
IPC分类号： A61K31/205 , C07C229/26 , A61P17/00
CPC分类号： C07C235/10 , C07C233/36 , C07C271/02
摘要： The present invention covers zwitterionic, non-surface-active compounds in the form of carboxymethylated, short-chain dialkylaminoalkylamides and use thereof as therapeutic agent.
摘要翻译： 本发明涵盖羧甲基化短链二烷基氨基烷基酰胺形式的两性离子，非表面活性化合物及其作为治疗剂的用途。
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3.发明申请公开(公告)号：US20070015681A1
公开(公告)日：2007-01-18
申请号：US11523258
申请日：2006-09-19
申请人： Petra Allef , Uwe Begoihn , Burghard Gruning , Ralf Klein , Jorg Peggau
发明人： Petra Allef , Uwe Begoihn , Burghard Gruning , Ralf Klein , Jorg Peggau
IPC分类号： C11D17/00
CPC分类号： C07C231/12 , C07C233/36 , C11D1/90
摘要： The invention relates to a process for preparing highly concentrated flowable and pumpable aqueous solutions of betaines by quaternization of compounds containing tertiary amine nitrogen with ω-halocarboxylic acids by known processes, wherein 0.1 to less than 3% by weight, preferably 0.1 to 1% by weight, based on the end product, of one or more micellar thickeners are added to the reaction mixture before or during the quaternization reaction.
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4.发明申请Process for the preparation of highly concentrated flowable aqueous solutions of betaines 有权制备甜菜碱高度浓缩的可流动水溶液的方法公开(公告)号：US20060128599A1
公开(公告)日：2006-06-15
申请号：US11281825
申请日：2005-11-17
申请人： Petra Allef , Uwe Begoihn , Burghard Gruning , Ralf Klein , Jorg Peggau
发明人： Petra Allef , Uwe Begoihn , Burghard Gruning , Ralf Klein , Jorg Peggau
IPC分类号： C11D1/10
CPC分类号： C07C231/12 , C07C233/36 , C11D1/90
摘要： The invention relates to a process for preparing highly concentrated flowable and pumpable aqueous solutions of betaines by quaternization of compounds containing tertiary amine nitrogen with ω-halocarboxylic acids by known processes, wherein 0.1 to less than 3% by weight, preferably 0.1 to 1% by weight, based on the end product, of one or more micellar thickeners are added to the reaction mixture before or during the quaternization reaction.
摘要翻译： 本发明涉及通过已知方法将含有叔胺氮化合物与ω-卤代羧酸的化合物季铵化制备高浓度可流动和可泵送的甜菜碱水溶液的方法，其中通过已知方法将0.1至小于3重量％，优选0.1至1重量％ 基于最终产物的一种或多种胶束增稠剂的重量在季铵化反应之前或期间加入到反应混合物中。
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5.发明授权Aqueous liquid solution of a betaine with a solids content of at least 40% by weight 失效固体含量至少为40重量％的甜菜碱的水性液体溶液
公开(公告)号：US5354906A
公开(公告)日：1994-10-11
申请号：US016917
申请日：1993-02-12
IPC分类号： A61K8/00 , A61K8/34 , A61K8/36 , A61K8/365 , A61K8/40 , A61K8/42 , A61Q5/02 , B01F17/00 , B01F17/18 , C07C233/36 , C07C233/38 , C09K3/00 , C07C233/00
CPC分类号： C07C233/36 , B01F17/0042
摘要： An aqueous liquid solution of a betaine of the following general formula is disclosed ##STR1## in which R is an alkyl group of coconut fatty acids, preferably hydrogenated coconut fatty acids, or a fatty acid mixture which, on the average, corresponds to coconut fatty acids, wherein the solution has a solids content of at least 40% by weight, a pH of 5 to 8 and an aminoamide content of not more than 1% by weight, characterized by a content of 1 to 3% by weight, based on the solution, of one or more saturated fatty acids with, on the average, 8 to 18 carbon atoms or one or more unsaturated fatty acids with, on the average, 8 to 24 carbon atoms and 0 to 4% by weight of glycerin, based on the solution.
摘要翻译： 公开了以下通式的甜菜碱的水性液体溶液：其中R是椰子脂肪酸的烷基，优选氢化椰子脂肪酸或脂肪酸混合物，其平均相当于 至椰子脂肪酸，其中溶液的固体含量为至少40重量％，pH为5至8，氨基酰胺含量不超过1重量％，其特征在于含量为1至3重量％ 基于溶液，一种或多种具有平均8至18个碳原子的饱和脂肪酸或一种或多种不均匀脂肪酸，平均具有8至24个碳原子和0至4重量％ 甘油，基于溶液。
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6.发明授权公开(公告)号：US07297675B2
公开(公告)日：2007-11-20
申请号：US11523258
申请日：2006-09-19
申请人： Petra Allef , Uwe Begoihn , Burghard Grüning , Ralf Klein , Jörg Peggau
发明人： Petra Allef , Uwe Begoihn , Burghard Grüning , Ralf Klein , Jörg Peggau
CPC分类号： C07C231/12 , C07C233/36 , C11D1/90
摘要： The invention relates to a process for preparing highly concentrated flowable and pumpable aqueous solutions of betaines by quaternization of compounds containing tertiary amine nitrogen with ω-halocarboxylic acids by known processes, wherein 0.1 to less than 3% by weight, preferably 0.1 to 1% by weight, based on the end product, of one or more micellar thickeners are added to the reaction mixture before or during the quaternization reaction.
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7.发明授权Process for the preparation of highly concentrated flowable aqueous solutions of betaines 有权制备甜菜碱高度浓缩的可流动水溶液的方法公开(公告)号：US07163916B2
公开(公告)日：2007-01-16
申请号：US11281825
申请日：2005-11-17
申请人： Petra Allef , Uwe Begoihn , Burghard Grüning , Ralf Klein , Jörg Peggau
发明人： Petra Allef , Uwe Begoihn , Burghard Grüning , Ralf Klein , Jörg Peggau
CPC分类号： C07C231/12 , C07C233/36 , C11D1/90
摘要： The invention relates to a process for preparing highly concentrated flowable and pumpable aqueous solutions of betaines by quaternization of compounds containing tertiary amine nitrogen with ω-halocarboxylic acids by known processes, wherein 0.1 to less than 3% by weight, preferably 0.1 to 1% by weight, based on the end product, of one or more micellar thickeners are added to the reaction mixture before or during the quaternization reaction.
摘要翻译： 本发明涉及通过已知方法将含有叔胺氮化合物与ω-卤代羧酸的化合物季铵化制备高浓度可流动和可泵送的甜菜碱水溶液的方法，其中通过已知方法将0.1至小于3重量％，优选0.1至1重量％ 基于最终产物的一种或多种胶束增稠剂的重量在季铵化反应之前或期间加入到反应混合物中。
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