公开(公告)号：US20100036164A1

公开(公告)日：2010-02-11

申请号：US12535789

申请日：2009-08-05

申请人： Srinivas Areveli ,  Radha Krishna Singamsetty ,  Satish Kumar Vujjni ,  Vijaya Kumar Adla ,  Sreenadha Charyulu Kandala ,  Ganesh Varanasi ,  Subbareddy Peddireddy ,  Mohammed Azeezulla Baig

发明人： Srinivas Areveli ,  Radha Krishna Singamsetty ,  Satish Kumar Vujjni ,  Vijaya Kumar Adla ,  Sreenadha Charyulu Kandala ,  Ganesh Varanasi ,  Subbareddy Peddireddy ,  Mohammed Azeezulla Baig

IPC分类号： C07C231/00

CPC分类号： C07C315/06 ,  C07B2200/13 ,  C07C317/44

摘要： Preparation of armodafinil crystalline Form I. Also provided is armodafinil having about 30% or more by weight of particles with sizes greater than about 250 μm, and about 70% or less by weight of particles having sizes less than about 250 μm, wherein of the particles having sizes less than about 250 μm, about 50% of them have diameters less than about 50 μm.

摘要翻译： 臂状杆菌结晶形式I的制备。还提供了具有约30重量％或更多重量的尺寸大于约250μm的颗粒和约70重量％或更少的尺寸小于约250μm的颗粒的臂多巴尼，其中 尺寸小于约250μm的颗粒，其中约50％具有小于约50μm的直径。

公开(公告)号：US20110218360A1

公开(公告)日：2011-09-08

申请号：US13112146

申请日：2011-05-20

申请人： Praveen Cherukupally ,  Venkata Reddy Vajrala ,  Vijaya Kumar Adla ,  Srinivasulu Rangineni ,  Sundaralakshmi Kanniah

发明人： Praveen Cherukupally ,  Venkata Reddy Vajrala ,  Vijaya Kumar Adla ,  Srinivasulu Rangineni ,  Sundaralakshmi Kanniah

IPC分类号： C07C211/42 ,  C07C209/22 ,  C07C209/88 ,  C07C209/86

CPC分类号： C07C211/42 ,  C07C209/28 ,  C07C249/02 ,  C07C2602/08 ,  Y10T428/2982 ,  C07C251/20

摘要： The present invention relates to processes for the preparation of rasagiline mesylate. Also provided is rasagiline mesylate having 90 volume percent of the particles (D90) with sizes less than about 6 μm and processes for the preparation thereof.

摘要翻译： 本发明涉及制备甲磺酸雷沙吉兰的方法。 还提供了具有90体积％的尺寸小于约6μm的颗粒（D90）的甲磺酸雷沙吉兰和其制备方法。