Sulfatides for treatment of autoimmune disorders
    1.
    发明授权
    Sulfatides for treatment of autoimmune disorders 有权
    硫酸酯治疗自身免疫性疾病

    公开(公告)号:US08044029B2

    公开(公告)日:2011-10-25

    申请号:US11529793

    申请日:2006-09-28

    CPC classification number: A61K31/7032 A61K31/7024

    Abstract: Disclosed herein are methods for the treatment of autoimmune or immune related diseases or disorders. Also disclosed are methods for treating such autoimmune or immune related diseases or disorders with the administration of sulfatides. Also disclosed herein are methods of treating autoimmune or immune related diseases or disorders by administering an amount of a sulfatide to the body of a patient effective to reduce or prevent the symptoms of the autoimmune or immune related disease or disorder.

    Abstract translation: 本文公开了治疗自身免疫或免疫相关疾病或病症的方法。 还公开了通过施用硫苷脂来治疗这种自身免疫性或免疫相关疾病或病症的方法。 本文还公开的是通过向患者的身体施用一定量的硫苷脂来有效减少或预防自身免疫或免疫相关疾病或病症的症状来治疗自身免疫或免疫相关疾病或病症的方法。

    PREVENTION OF HEPATIC ISCHEMIC REPERFUSION INJURY BY ADMINISTRATION OF SULFATIDES
    2.
    发明申请
    PREVENTION OF HEPATIC ISCHEMIC REPERFUSION INJURY BY ADMINISTRATION OF SULFATIDES 审中-公开
    通过管理磺胺类预防肝脏间歇性再灌注损伤

    公开(公告)号:US20110118197A1

    公开(公告)日:2011-05-19

    申请号:US12938315

    申请日:2010-11-02

    CPC classification number: A61K31/7024 A61K31/7028

    Abstract: Hepatic ischemic reperfusion injury is a major complication of liver transplantation, resectional hepatic surgeries, trauma surgery and shock. Disclosed herein are methods for the prevention and treatment of ischemia and reperfusion injury with the administration of sulfatides. Also disclosed herein are methods of preventing and treating hepatic reperfusion injury by administering an amount of a sulfatide to the body of a patient effective to reduce or prevent the symptoms of the injury.

    Abstract translation: 肝缺血再灌注损伤是肝移植,肝切除手术,创伤手术和休克的主要并发症。 本文公开了通过施用硫苷脂来预防和治疗缺血和再灌注损伤的方法。 本文还公开了通过向有效减少或预防损伤症状的患者体内施用一定量的硫苷脂来预防和治疗肝再灌注损伤的方法。

    PREVENTION AND TREATMENT OF INFLAMMATORY CONDITIONS
    3.
    发明申请
    PREVENTION AND TREATMENT OF INFLAMMATORY CONDITIONS 有权
    预防和治疗炎症条件

    公开(公告)号:US20140187504A1

    公开(公告)日:2014-07-03

    申请号:US14128566

    申请日:2012-06-22

    Abstract: The present embodiments relate to methods for the prevention and treatment of inflammatory conditions such as alcoholic liver disease (ALD). More specifically the present embodiments relate to the prevention and treatment of ALD through the administration of an Retinoic Acid Receptor (RAR) agonist. Some embodiments relate to use of tazarotene in the prevention and treatment of alcohol-induced liver injury, alcohol-related liver disease, fatty liver disease, hepatic steatosis, alcoholic hepatitis or alcoholic cirrhosis.

    Abstract translation: 本实施方案涉及预防和治疗诸如酒精性肝病(ALD)的炎性病症的方法。 更具体地,本实施方案涉及通过施用视黄酸受体(RAR)激动剂来预防和治疗ALD。 一些实施方案涉及他扎罗汀在预防和治疗酒精性肝损伤,酒精相关性肝病,脂肪肝疾病,肝脂肪变性,酒精性肝炎或酒精性肝硬化中的用途。

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