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公开(公告)号:US07122201B2
公开(公告)日:2006-10-17
申请号:US10183599
申请日:2002-06-26
申请人: Jianwei Yu , Pui-Ho Yuen , Virginia Paulate
发明人: Jianwei Yu , Pui-Ho Yuen , Virginia Paulate
IPC分类号: A61F2/02
CPC分类号: A61K47/26 , A61K9/0019 , A61K47/10 , A61K47/183
摘要: Compositions and methods are provided for reducing adverse reactions as a result of parenteral administration of certain phenothiazine derivatives such as promethazine, including promethazine hydrochloride. The active compound may be admixed with an effective amount of one or more non-ionic surfactants and at least one amino acid and/or one polyol prior to administration to an animal such as a mammal.