公开(公告)号：US5169759A

公开(公告)日：1992-12-08

申请号：US644609

申请日：1991-01-23

申请人： Tillmann Faust ,  Joachim Meyer ,  Georg Wellinghoff ,  Walter Gosele ,  Christoph Martin ,  Johannes Grimmer

发明人： Tillmann Faust ,  Joachim Meyer ,  Georg Wellinghoff ,  Walter Gosele ,  Christoph Martin ,  Johannes Grimmer

IPC分类号： C07D475/14 ,  C12P17/18 ,  C12P25/00

CPC分类号： C12P25/00

摘要： Riboflavin is removed from fermentation suspensions by them being heated at from 50.degree. to 90.degree. C. for from 1 to 3 hours, than cooled to from 0.degree. to 30.degree. C. over a period of from 1 to 5 hours, and subsequently being centrifuged to give a sediment fraction and liquid fraction in such a way that the sediment fraction contains predominantly riboflavin crystals as solid, and the liquid fraction contains virtually no crystalline riboflavin, and, where appropriate, resuspending the sediment fraction in from 0.5 to 2 parts by volume of water per part by volume of sediment fraction and repeating procedure c.

摘要翻译： 将核黄素从发酵悬浮液中除去，在50〜90℃下加热1〜3小时，冷却至0〜30℃，时间为1〜5小时，随后为 离心分离以得到沉淀物部分和液体部分，使得沉淀物部分主要含有核黄素晶体作为固体，并且液体部分几乎不含结晶核黄素，并且在适当情况下将沉降物组分重悬于0.5至2份中 每部分体积的沉淀物含量的水量和重复程序c。