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公开(公告)号:US06465627B2
公开(公告)日:2002-10-15
申请号:US08687691
申请日:1996-07-26
申请人: Edward R. B. McCabe , Weiwen Guo , Thomas P. Burris , Eric Vilain
发明人: Edward R. B. McCabe , Weiwen Guo , Thomas P. Burris , Eric Vilain
IPC分类号: C12N1511
CPC分类号: C07K14/721 , A61K38/00 , A61K48/00 , C07K14/70567 , C12N2799/022
摘要: The invention provides a DAX-1 protein molecule having the amino acid sequence beginning with methionine at position 1 and ending with isoleucine at position 470 as shown in FIG. 12. The invention further provides the genomic nucleic acid sequence for DAX-1, including intron, exons and a promoter region. Additionally, the invention provides methods for using and making the DAX-1 protein and DAX-1 nucleic acid molecules.
摘要翻译: 本发明提供了一种DAX-1蛋白质分子,其具有如图1所示的氨基酸序列,起始于位置1处的甲硫氨酸和位置470的异亮氨酸结束。 本发明还提供了DAX-1的基因组核酸序列,包括内含子,外显子和启动子区。 此外,本发明提供了使用和制备DAX-1蛋白和DAX-1核酸分子的方法。