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公开(公告)号：US08435993B2
公开(公告)日：2013-05-07
申请号：US13312540
申请日：2011-12-06
IPC分类号： A01N43/58 , A01N43/60 , A01N43/40 , A61K31/495 , A61K31/50 , A61K31/445 , A61K51/00 , C07D211/00 , C07D401/00 , C07D241/36 , C07D471/00 , A61M36/14
CPC分类号： C07D487/04 , A61K31/451 , A61K31/453 , A61K31/7088 , A61K39/3955 , C07D403/04 , C07K16/28
摘要： The present invention includes compositions that are useful in preventing or treating metastasis in a subject diagnosed with cancer. The present invention also includes methods of preventing or treating metastasis in a subject diagnosed with cancer, wherein the method comprises administering to the subject in need thereof an effective amount of a pharmaceutical formulation comprising at least one pharmaceutically acceptable carrier and at least one CX3CR1 or fractalkine antagonist.
摘要翻译： 本发明包括可用于预防或治疗患有癌症的受试者的转移的组合物。 本发明还包括预防或治疗患有癌症的受试者的转移的方法，其中所述方法包括向有需要的受试者施用有效量的药物制剂，其包含至少一种药学上可接受的载体和至少一种CX3CR1或fractalkine 拮抗剂。
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公开(公告)号：US20120141471A1
公开(公告)日：2012-06-07
申请号：US13312540
申请日：2011-12-06
IPC分类号： A61K39/395 , A61K31/4985 , C07K16/28 , A61K31/4468 , A61P35/04 , A61K31/7088 , A61K31/451 , C07D487/04 , C07K16/24
CPC分类号： C07D487/04 , A61K31/451 , A61K31/453 , A61K31/7088 , A61K39/3955 , C07D403/04 , C07K16/28
摘要： The present invention includes compositions that are useful in preventing or treating metastasis in a subject diagnosed with cancer. The present invention also includes methods of preventing or treating metastasis in a subject diagnosed with cancer, wherein the method comprises administering to the subject in need thereof an effective amount of a pharmaceutical formulation comprising at least one pharmaceutically acceptable carrier and at least one CX3CR1 or fractalkine antagonist.
摘要翻译： 本发明包括可用于预防或治疗患有癌症的受试者的转移的组合物。 本发明还包括预防或治疗患有癌症的受试者的转移的方法，其中所述方法包括向有需要的受试者施用有效量的药物制剂，其包含至少一种药学上可接受的载体和至少一种CX3CR1或fractalkine 拮抗剂。
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