摘要:
Automation of microscopic pathological diagnosis relies on digital image quality, which, in turn, affects the rates of false positive and negative cellular objects designated as abnormalities. Cytogenetic biodosimetry is a genotoxic assay that detects dicentric chromosomes (DCs) arising from exposure to ionizing radiation. The frequency of DCs is related to radiation dose received, so the inferred radiation dose depends on the accuracy of DC detection. To improve this accuracy, image segmentation methods are used to rank high quality cytogenetic images and eliminate suboptimal metaphase cell data in a sample based on novel quality measures. When sufficient numbers of high quality images are found, the microscope system is directed to terminate metaphase image collection for a sample. The International Atomic Energy Agency recommends at least 500 images be used to estimate radiation dose, however often many more images are collected in order to select the metaphase cells with good morphology for analysis. Improvements in DC recognition increase the accuracy of dose estimates, by reducing false positive (FP) DC detection. A set of chromosome morphology segmentation methods selectively filtered out false DCs, arising primarily from extended prometaphase chromosomes, sister chromatid separation and chromosome fragmentation. This reduced FPs by 55% and was highly specific to the abnormal structures (≥97.7%). Additional procedures were then developed to fully automate image review, resulting in 6 image-level filters that, when combined, selectively remove images with consistently unparsable or incorrectly segmented chromosome morphologies. Overall, these filters can eliminate half of the FPs detected by manual image review. Optimal image selection and FP DCs are minimized by combining multiple feature based segmentation filters and a novel image sorting procedure based on the known distribution of chromosome lengths. Consequently, the average dose estimation error was reduced from 0.4 Gy to
摘要:
We describe a motion compensated frame interpolation apparatus and method that includes a motion vector interpolation module for an object and uncovered area to generate information for motion vectors that cross interpolated pixels in object and/or uncovered areas. A motion vector interpolation module for a covered area generates information for motion vectors that cross interpolated pixels in covered areas. A motion vector counter records a number of motion vectors that cross an interpolated pixel. A buffer for motion vector interpolation buffers the information for motion vectors that cross interpolated pixels in the object and/or uncovered areas and the covered areas. And a video data interpolation module generates video data of the interpolated pixels in object and/or uncovered areas and the covered areas.
摘要:
An automated microscope system is described that detects dicentric chromosomes (DCs) in metaphase cells arising from exposure to ionizing radiation. The radiation dose depends on the accuracy of DC detection. Accuracy is increased using image segmentation methods are used to rank high quality cytogenetic images and eliminate suboptimal metaphase cell data in a sample based on novel quality measures. When a sufficient number of high quality images are detected, the microscope system is directed to terminate metaphase image collection for a sample. The microscope system integrates image selection procedures that control an automated digitally controlled microscope with the analysis of acquired metaphase cell images to accurately determine radiation dose. Early termination of image acquisition reduces sample processing time without compromising accuracy. This approach constitutes a reliable and scalable solution that will be essential for analysis of large numbers of potentially exposed individuals.
摘要:
An automated microscope system is described that detects dicentric chromosomes (DCs) in metaphase cells arising from exposure to ionizing radiation. The radiation dose depends on the accuracy of DC detection. Accuracy is increased using image segmentation methods are used to rank high quality cytogenetic images and eliminate suboptimal metaphase cell data in a sample based on novel quality measures. When a sufficient number of high quality images are detected, the microscope system is directed to terminate metaphase image collection for a sample. The microscope system integrates image selection procedures that control an automated digitally controlled microscope with the analysis of acquired metaphase cell images to accurately determine radiation dose. Early termination of image acquisition reduces sample processing time without compromising accuracy. This approach constitutes a reliable and scalable solution that will be essential for analysis of large numbers of potentially exposed individuals.
摘要:
Burners, such as all kinds of fuel oil, gas and powdered coal, have combustion chambers for stabilizing combustion and air distribution. The invention discloses a forced reversal combustion chamber, which has a combustion chamber body, configured as a hollow cavity a plurality of swirl vanes for delivering combustion air into the combustion chamber, correspondingly provided on interior side of flame outlet end of the combustion chamber; in the middle of inner end of the combustion chamber, a fuel nozzle is provided, which inserts into interior wall of the combustion chamber and outlet of which extends through the interior wall of the combustion chamber; outlet end of the combustion chamber after mixing air and fuel is flame outlet. The forced reversal combustion chamber of the invention can provide good flame stabilization, high burn-off rate of fuel and good environmental protection property.
摘要:
We describe a motion compensated frame interpolation apparatus and method that includes a motion vector interpolation module for an object and uncovered area to generate information for motion vectors that cross interpolated pixels in object and/or uncovered areas. A motion vector interpolation module for a covered area generates information for motion vectors that cross interpolated pixels in covered areas. A motion vector counter records a number of motion vectors that cross an interpolated pixel. A buffer for motion vector interpolation buffers the information for motion vectors that cross interpolated pixels in the object and/or uncovered areas and the covered areas. And a video data interpolation module generates video data of the interpolated pixels in object and/or uncovered areas and the covered areas.
摘要:
A combustion control method for a burner comprises: the fuel supplying means outputs a given amount of fuel oil to the fuel oil atomizing means; the fuel atomizing means sprays fuel atomized gas; said gas is ignited by the igniter; the amount of air is sent to facilitate burning by the air blowing means; the outputting flow rate of fuel oil and the flow rate of air are adjusted automatically, simultaneously and proportionally by controlling the rotating speed of the electric motors of the fuel supplying means and the air blowing means. An autocontrol burner comprises a main body, an oil pump (2), a blower fan (1), a spray gun (9) and an ignition gun (10), and further comprises a programmable control unit (18), motor speed controller (16, 17) and a signal acquisition assembly. The output port of the signal acquisition assembly is connected with the input port of the programmable control unit (18). The oil pump (2) and the blower fan (1) are connected with the programmable control unit (18) by the motor speed controller (16, 17).
摘要:
Automation of microscopic pathological diagnosis relies on digital image quality, which, in turn, affects the rates of false positive and negative cellular objects designated as abnormalities. Cytogenetic biodosimetry is a genotoxic assay that detects dicentric chromosomes (DCs) arising from exposure to ionizing radiation. The frequency of DCs is related to radiation dose received, so the inferred radiation dose depends on the accuracy of DC detection. To improve this accuracy, image segmentation methods are used to rank high quality cytogenetic images and eliminate suboptimal metaphase cell data in a sample based on novel quality measures. When sufficient numbers of high quality images are found, the microscope system is directed to terminate metaphase image collection for a sample. The International Atomic Energy Agency recommends at least 500 images be used to estimate radiation dose, however often many more images are collected in order to select the metaphase cells with good morphology for analysis. Improvements in DC recognition increase the accuracy of dose estimates, by reducing false positive (FP) DC detection. A set of chromosome morphology segmentation methods selectively filtered out false DCs, arising primarily from extended prometaphase chromosomes, sister chromatid separation and chromosome fragmentation. This reduced FPs by 55% and was highly specific to the abnormal structures (≥97.7%). Additional procedures were then developed to fully automate image review, resulting in 6 image-level filters that, when combined, selectively remove images with consistently unparsable or incorrectly segmented chromosome morphologies. Overall, these filters can eliminate half of the FPs detected by manual image review. Optimal image selection and FP DCs are minimized by combining multiple feature based segmentation filters and a novel image sorting procedure based on the known distribution of chromosome lengths. Consequently, the average dose estimation error was reduced from 0.4 Gy to
摘要:
An apparatus has a neighbor motion vector module arranged to receive motion vector data for blocks that neighbor a current pixel and select a predetermined number of block motion vectors, at least two pixel motion vector modules arranged to receive the block motion vector data and to produce interpolated pixel motion vector data, a weighting module configured to produce a weighting for the interpolated pixel motion vector data from the motion vector modules, and a blending module to blend the interpolated pixel motion vector data according to the weighting and to produce pixel output data for the current pixel.
摘要:
A combustion control method for a burner comprises: the fuel supplying means outputs a given amount of fuel oil to the fuel oil atomizing means; the fuel atomizing means sprays fuel atomized gas; said gas is ignited by the igniter; the amount of air is sent to facilitate burning by the air blowing means; the outputting flow rate of fuel oil and the flow rate of air are adjusted automatically, simultaneously and proportionally by controlling the rotating speed of the electric motors of the fuel supplying means and the air blowing means. An autocontrol burner comprises a main body, an oil pump (2), a blower fan (1), a spray gun (9) and an ignition gun (10), and further comprises a programmable control unit (18), motor speed controller (16,17) and a signal acquisition assembly. The output port of the signal acquisition assembly is connected with the input port of the programmable control unit (18). The oil pump (2) and the blower fan (1) are connected with the programmable control unit (18) by the motor speed controller (16, 17).