公开(公告)号：US5695972A

公开(公告)日：1997-12-09

申请号：US653042

申请日：1996-05-24

申请人： Yasuichiro Suga ,  Masato Ikeda ,  Kuniki Kino

发明人： Yasuichiro Suga ,  Masato Ikeda ,  Kuniki Kino

IPC分类号： C12N1/20 ,  C12P13/06 ,  C12R1/19 ,  C12N1/00 ,  C12P13/08

CPC分类号： C12N1/20 ,  C12P13/06 ,  Y10S435/849

摘要： The present invention provide a method for the industrial production of L-isoleucine which is useful as pharmaceuticals, foods, feed additives and the like. The method comprises cultivating in a nutrient medium a microorganism belonging to the genus Escherichia which is capable of rapidly growing in a medium containing L-homoserine as the single nitrogen source and has an ability to produce L-isoleucine in the medium, producing and accumulate L-isoleucine in a culture and recovering L-isoleucine therefrom.

摘要翻译： 本发明提供了用作药物，食品，饲料添加剂等的L-异亮氨酸工业化生产的方法。 该方法包括在营养培养基中培养属于埃希氏菌属的微生物，其能够在含有L-高丝氨酸的培养基中作为单一氮源快速生长，并且具有在培养基中产生L-异亮氨酸的能力，产生和积累L - 异亮氨酸，从其中回收L-异亮氨酸。