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公开(公告)号：US09320622B2
公开(公告)日：2016-04-26
申请号：US13988870
申请日：2011-11-25
IPC分类号： C22C38/22 , C22C38/02 , C22C38/04 , A61F2/82 , C22C38/00 , C22C38/26 , C22C38/28 , A61L31/02
CPC分类号： A61F2/82 , A61L31/022 , C22C38/001 , C22C38/002 , C22C38/02 , C22C38/04 , C22C38/06 , C22C38/22 , C22C38/26 , C22C38/28 , C22C38/32 , C22C38/44
摘要： A nickel-free stainless steel stent using a stainless steel which does not substantially contain Ni in the stainless steel, has a metal allergy onset-preventing effect, and is excellent in terms of precision workability, strength, and ductility, is provided. The nickel-free stainless steel stent is characterized by using a stainless steel containing, as a chemical composition, from 15 to 30% by mass of Cr, from 0.97 to 2% by mass of Mo, and from 0.5 to 1% by mass of N, with the remainder being Fe, and optionally containing inevitable impurities.
摘要翻译： 使用不锈钢不含镍的不含镍的不锈钢支架，具有金属过敏起效防止效果，并且在精加工性，强度和延展性方面优异。 无镍不锈钢支架的特征在于，使用含有15〜30质量％的Cr，0.97〜2质量％的Mo和0.5〜1质量％的作为化学组成的不锈钢， N，其余为Fe，并且任选地含有不可避免的杂质。
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公开(公告)号：US20130304184A1
公开(公告)日：2013-11-14
申请号：US13988870
申请日：2011-11-25
IPC分类号： A61F2/82
CPC分类号： A61F2/82 , A61L31/022 , C22C38/001 , C22C38/002 , C22C38/02 , C22C38/04 , C22C38/06 , C22C38/22 , C22C38/26 , C22C38/28 , C22C38/32 , C22C38/44
摘要： A nickel-free stainless steel stent using a stainless steel which does not substantially contain Ni in the stainless steel, has a metal allergy onset-preventing effect, and is excellent in terms of precision workability, strength, and ductility, is provided. The nickel-free stainless steel stent is characterized by using a stainless steel containing, as a chemical composition, from 15 to 30% by mass of Cr, from 0.97 to 2% by mass of Mo, and from 0.5 to 1% by mass of N, with the remainder being Fe, and optionally containing inevitable impurities.
摘要翻译： 使用不锈钢不含镍的不含镍的不锈钢支架，具有金属过敏起效防止效果，并且在精加工性，强度和延展性方面优异。 无镍不锈钢支架的特征在于，使用含有15〜30质量％的Cr，0.97〜2质量％的Mo和0.5〜1质量％的作为化学组成的不锈钢， N，其余为Fe，并且任选地含有不可避免的杂质。
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公开(公告)号：US20130245240A1
公开(公告)日：2013-09-19
申请号：US13989279
申请日：2011-11-24
申请人： Tetsushi Taguchi , Makoto Sasaki , Yasuyuki Katada
发明人： Tetsushi Taguchi , Makoto Sasaki , Yasuyuki Katada
CPC分类号： C07K17/14 , A61F2/82 , A61L31/022 , A61L31/16 , A61L2300/414 , A61L2300/426
摘要： Provided is a bio-hybrid material that does not cause elution of nickel ions and has an excellent endothelialization ability, a production method therefor, and a stent. The bio-hybrid material (101) used includes an alloy part (11) free of Ni, an organic acid (12) having two or more active esters, and a cytokine (13). The alloy part (11) free of Ni forms an ester bond with the organic acid (12), and the organic acid (12) and the cytokine (13) are immobilized via an amide bond.
摘要翻译： 提供了不引起镍离子洗脱并具有优异的内皮化能力的生物混合材料，其制备方法和支架。 使用的生物混合材料（101）包括不含Ni的合金部分（11），具有两种以上活性酯的有机酸（12）和细胞因子（13）。 不含Ni的合金部分（11）与有机酸（12）形成酯键，有机酸（12）和细胞因子（13）通过酰胺键固定。
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公开(公告)号：US20130045277A1
公开(公告)日：2013-02-21
申请号：US13576718
申请日：2011-02-01
CPC分类号： A61L31/10 , A61L31/16 , A61L2300/602
摘要： Disclosed is a biocompatible device surface-coated on the base material thereof with a biocompatible polymer layer having antithrombogenicity and endothelialization activity, and embedded in or attached to a living body for use. The polymer layer comprises a polymer matrix formed by the crosslinking of a cell-adhesive peptide-containing polymer.
摘要翻译： 公开了一种在其基材上表面涂覆有生物相容性聚合物层的生物相容性装置，其具有抗血栓形成和内皮化活性，并且嵌入或附着于生物体使用。 聚合物层包含通过含细胞粘着肽的聚合物交联而形成的聚合物基质。
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公开(公告)号：US09428588B2
公开(公告)日：2016-08-30
申请号：US13989279
申请日：2011-11-24
申请人： Tetsushi Taguchi , Makoto Sasaki , Yasuyuki Katada
发明人： Tetsushi Taguchi , Makoto Sasaki , Yasuyuki Katada
CPC分类号： C07K17/14 , A61F2/82 , A61L31/022 , A61L31/16 , A61L2300/414 , A61L2300/426
摘要： Provided is a bio-hybrid material that does not cause elution of nickel ions and has an excellent endothelialization ability, a production method therefor, and a stent. The bio-hybrid material (101) used includes an alloy part (11) free of Ni, an organic acid (12) having two or more active esters, and a cytokine (13). The alloy part (11) free of Ni forms an ester bond with the organic acid (12), and the organic acid (12) and the cytokine (13) are immobilized via an amide bond.
摘要翻译： 提供了不引起镍离子洗脱并具有优异的内皮化能力的生物混合材料，其制备方法和支架。 使用的生物混合材料（101）包括不含Ni的合金部分（11），具有两种以上活性酯的有机酸（12）和细胞因子（13）。 不含Ni的合金部分（11）与有机酸（12）形成酯键，有机酸（12）和细胞因子（13）通过酰胺键固定。
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