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公开(公告)号:US20120088245A1
公开(公告)日:2012-04-12
申请号:US13126695
申请日:2009-10-30
申请人: Jerome I. Rotter , Kent D. Taylor , Xiuqing Guo , Mark O. Goodarzi , Yii-Der I. Chen , Leslie Raffel , Thomas A. Buchanan , Anny Xiang
发明人: Jerome I. Rotter , Kent D. Taylor , Xiuqing Guo , Mark O. Goodarzi , Yii-Der I. Chen , Leslie Raffel , Thomas A. Buchanan , Anny Xiang
IPC分类号: C12Q1/68
CPC分类号: G01N33/6875 , C12Q1/6883 , C12Q2600/106 , C12Q2600/156 , C12Q2600/172 , G01N33/6893 , G01N2333/92 , G01N2800/042
摘要: Methods of diagnosing susceptibility to metabolic insulin resistance and other related conditions are disclosed. The method provides means of diagnosing susceptibility to insulin resistance in Hispanic Americans by determining the presence of a risk haplotype at the LPL locus, the LPIN1 locus, and/or elevated levels of gamma-glutamyl transferase.
摘要翻译: 公开了诊断代谢性胰岛素抵抗的易感性及其他相关病症的方法。 该方法通过确定在LPL基因座,LPIN1基因座和/或γ-谷氨酰转移酶水平升高的风险单倍型的存在来提供诊断西班牙裔美国人胰岛素抵抗的易感性的方法。