公开(公告)号：US20110129437A1

公开(公告)日：2011-06-02

申请号：US12956179

申请日：2010-11-30

Applicant: Ying-nan TSAI ,  Ken-Yuan Chang ,  Fa Chen Chi ,  Po-Yang Chen ,  Cheng-Tar Wu

Inventor： Ying-nan TSAI ,  Ken-Yuan Chang ,  Fa Chen Chi ,  Po-Yang Chen ,  Cheng-Tar Wu

IPC: A61K31/785 ,  A61P7/02 ,  C08F222/40 ,  C08G71/04

CPC classification number: C08G18/7671 ,  A61K31/785 ,  C08G18/3829 ,  C08G18/4833 ,  C08G18/6685 ,  C08G18/755 ,  C08G18/758

Abstract: A platelet adhesion-resistant material is provided, which includes polytriuret-urethane consisting essentially of repeating structural units of formulae (I) to (III) in a random order, in which when the total number of the three repeating structural units in the polytriuret-urethane is 100, the number of the repeating structural units (I) is about 5 to about 50: in which each R independently represents a C2-C16 alkylene group, a C6-C30 aromatic group, a C6-C30 alicyclic group; n is an integer of 2 to 16; and R1 represents —(OCmH2m)p, in which m is an integer of 2 to 5, and p is an integer of 3 to 150.

Abstract translation: 提供了一种抗血小板粘合性材料，其包括基本上由随机顺序的式（I）至（III）的重复结构单元组成的多核苷酸 - 氨基甲酸酯，其中当多萜类化合物的三个重复结构单元的总数， 氨基甲酸酯为100，重复结构单元（I）的数量为约5至约50：其中各R独立地表示C2-C16亚烷基，C6-C30芳族基团，C6-C30脂环族基团; n为2〜16的整数。 并且R 1表示 - （OC m H 2n）p，其中m为2至5的整数，p为3至150的整数。

公开(公告)号：US08771571B2

公开(公告)日：2014-07-08

申请号：US13051236

申请日：2011-03-18

Applicant: Jo-Wei Huang ,  Chia-Chang Liu ,  Ying-Nan Tsai

Inventor： Jo-Wei Huang ,  Chia-Chang Liu ,  Ying-Nan Tsai

IPC: D01D1/02 ,  D04H13/00 ,  C08G69/08 ,  C08G69/10

CPC classification number: C08G69/08 ,  C08G69/10 ,  D01F1/10 ,  D01F6/68 ,  D04H1/30 ,  D04H1/4266 ,  D04H13/00 ,  D06M11/07 ,  D06M11/11 ,  D06M11/70 ,  D06M16/00 ,  Y10T428/2913 ,  Y10T442/2525 ,  Y10T442/696

Abstract: A method for preparing a polyglutamic acid (γ-PGA) fiber having antibacterial and water absorption properties is provided. The method includes providing a γ-PGA fiber and immersing it in a sodium hypochlorite solution. A relation exists between an immersing time T of the γ-PGA fiber and a concentration X of the sodium hypochlorite solution as shown in the formula below: 10.2≦(T−64.55X2+50X)≦15.2, wherein X is 0.006-0.4 wt %.

Abstract translation: 提供了具有抗菌吸水性的聚谷氨酸（γ-PGA）纤维的制造方法。 该方法包括提供γ-PGA纤维并将其浸入次氯酸钠溶液中。 如下式所示，γ-PGA纤维的浸渍时间T和次氯酸钠溶液的浓度X之间存在关系：10.2＆nlE;（T-64.55X2 + 50X）＆lt; 15;其中X为0.006- 0.4重量％。

公开(公告)号：US20120083179A1

公开(公告)日：2012-04-05

申请号：US13051236

申请日：2011-03-18

Applicant: Jo-Wei Huang ,  Chia-Chang Liu ,  Ying-Nan Tsai

Inventor： Jo-Wei Huang ,  Chia-Chang Liu ,  Ying-Nan Tsai

IPC: D04H13/00 ,  B29B9/06 ,  C08G61/12

CPC classification number: C08G69/08 ,  C08G69/10 ,  D01F1/10 ,  D01F6/68 ,  D04H1/30 ,  D04H1/4266 ,  D04H13/00 ,  D06M11/07 ,  D06M11/11 ,  D06M11/70 ,  D06M16/00 ,  Y10T428/2913 ,  Y10T442/2525 ,  Y10T442/696

Abstract: A method for preparing a polyglutamic acid (γ-PGA) fiber having antibacterial and water absorption properties is provided. The method includes providing a γ-PGA fiber and immersing it in a sodium hypochlorite solution. A relation exists between an immersing time T of the γ-PGA fiber and a concentration X of the sodium hypochlorite solution as shown in the formula below: 10.2≦(T−64.55X2+50X)≦15.2, wherein X is 0.006-0.4 wt %.

Abstract translation: 提供了具有抗菌吸水性的聚谷氨酸（γ-PGA）纤维的制备方法。 该方法包括提供γ-PGA纤维并将其浸入次氯酸钠溶液中。 如下式所示，γ-PGA纤维的浸渍时间T和次氯酸钠溶液的浓度X之间存在关系：10.2＆nlE;（T-64.55X2 + 50X）＆lt; 15;其中X为0.006- 0.4重量％。

公开(公告)号：US20120082638A1

公开(公告)日：2012-04-05

申请号：US13098788

申请日：2011-05-02

Applicant: Chun-Yi Li ,  Ken-Yuan Chang ,  Chia-Chang Liu ,  Ying-Nan Tsai

Inventor： Chun-Yi Li ,  Ken-Yuan Chang ,  Chia-Chang Liu ,  Ying-Nan Tsai

IPC: A01N37/44 ,  A01P1/00 ,  C08G69/10

CPC classification number: C08G69/10 ,  A01N37/46 ,  A01N59/00 ,  A01N2300/00

Abstract: A water-soluble and biodegradable antimicrobial agent is provided, comprising a polymer composed of a segment A and a segment B, in which, the segment A has the following formula I: the segment B has the following formula II: wherein the segment A and the segment B in the polymer have a molar ratio of 1:0.007-1.2, and n is 0 or 1, m is an integer of 0-2, m+n≠0, X is H, Na, K, NH4, ½Ca, or ½Mg, and Y is Cl, Br, or I.

Abstract translation: 提供了一种水溶性和可生物降解的抗微生物剂，其包含由段A和段B组成的聚合物，其中段A具有下式I：段B具有下式II：其中段A和 聚合物中的链段B的摩尔比为1:0.007-1.2，n为0或1，m为0-2的整数，m + n≠0，X为H，Na，K，NH 4，½Ca ，或½Mg，Y是Cl，Br或I.

公开(公告)号：US08530405B2

公开(公告)日：2013-09-10

申请号：US13098814

申请日：2011-05-02

Applicant: Chun-Yi Li ,  Ken-Yuan Chang ,  Chia-Chang Liu ,  Ying-Nan Tsai

Inventor： Chun-Yi Li ,  Ken-Yuan Chang ,  Chia-Chang Liu ,  Ying-Nan Tsai

IPC: A01N37/18 ,  A61K38/00 ,  A61P31/00

CPC classification number: A01N37/46 ,  A01N59/00 ,  A01N2300/00

Abstract: A method of preparing a water-soluble and biodegradable antimicrobial agent is provided. The method includes treating a polypeptide compound with sodium hypochlorite for at least 1 min, such that the polypeptide compound has at least one N-halamine group and has good antimicrobial effect. By using the method of the present invention, a chemical synthesis process is not required and an organic solvent is not required either, and thus, an antimicrobial agent having high water solubility, biodegradability, non-toxicity, good sterilization effect, and regeneration can be prepared with reduced harms to the environment.

Abstract translation: 提供了制备水溶性和可生物降解的抗微生物剂的方法。 该方法包括用次氯酸钠处理多肽化合物至少1分钟，使得多肽化合物具有至少一个N-卤代胺基团并且具有良好的抗微生物作用。 通过使用本发明的方法，不需要化学合成方法，也不需要有机溶剂，因此具有高水溶性，生物降解性，无毒性，良好灭菌效果和再生的抗菌剂可以是 准备减少对环境的危害。

公开(公告)号：US08778325B2

公开(公告)日：2014-07-15

申请号：US13098788

申请日：2011-05-02

Applicant: Chun-Yi Li ,  Ken-Yuan Chang ,  Chia-Chang Liu ,  Ying-Nan Tsai

Inventor： Chun-Yi Li ,  Ken-Yuan Chang ,  Chia-Chang Liu ,  Ying-Nan Tsai

IPC: A61K31/74 ,  A61K47/48 ,  A01N37/46 ,  C08G69/10

CPC classification number: C08G69/10 ,  A01N37/46 ,  A01N59/00 ,  A01N2300/00

Abstract: A water-soluble and biodegradable antimicrobial agent is provided, comprising a polymer composed of a segment A and a segment B, in which, the segment A has the following formula I: the segment B has the following formula II: wherein the segment A and the segment B in the polymer have a molar ratio of 1:0.007-1.2, and n is 0 or 1, m is an integer of 0-2, m+n≠0, X is H, Na, K, NH4, ½Ca, or ½Mg, and Y is Cl, Br, or I.

Abstract translation: 提供了一种水溶性和可生物降解的抗微生物剂，其包含由段A和段B组成的聚合物，其中段A具有下式I：段B具有下式II：其中段A和 聚合物中的链段B的摩尔比为1:0.007-1.2，n为0或1，m为0-2的整数，m + n≠0，X为H，Na，K，NH 4，½Ca ，或½Mg，Y是Cl，Br或I.

公开(公告)号：US20120083439A1

公开(公告)日：2012-04-05

申请号：US13098814

申请日：2011-05-02

Applicant: Chun-Yi Li ,  Ken-Yuan Chang ,  Chia-Chang Liu ,  Ying-Nan Tsai

Inventor： Chun-Yi Li ,  Ken-Yuan Chang ,  Chia-Chang Liu ,  Ying-Nan Tsai

IPC: A01N37/36 ,  A01P1/00

CPC classification number: A01N37/46 ,  A01N59/00 ,  A01N2300/00

Abstract: A method of preparing a water-soluble and biodegradable antimicrobial agent is provided. The method includes treating a polypeptide compound with sodium hypochlorite for at least 1 min, such that the polypeptide compound has at least one N-halamine group and has good antimicrobial effect. By using the method of the present invention, a chemical synthesis process is not required and an organic solvent is not required either, and thus, an antimicrobial agent having high water solubility, biodegradability, non-toxicity, good sterilization effect, and regeneration can be prepared with reduced harms to the environment.

Abstract translation: 提供了制备水溶性和可生物降解的抗微生物剂的方法。 该方法包括用次氯酸钠处理多肽化合物至少1分钟，使得多肽化合物具有至少一个N-卤代胺基团并且具有良好的抗微生物作用。 通过使用本发明的方法，不需要化学合成方法，也不需要有机溶剂，因此具有高水溶性，生物降解性，无毒性，良好灭菌效果和再生的抗微生物剂可以是 准备减少对环境的危害。