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公开(公告)号:US20090068110A1
公开(公告)日:2009-03-12
申请号:US11959783
申请日:2007-12-19
申请人: Yonglei Shang , Jean-Philippe F. Stephan , Yan Wu , Jiping Zha
发明人: Yonglei Shang , Jean-Philippe F. Stephan , Yan Wu , Jiping Zha
IPC分类号: A61K39/395 , C07K16/28 , C12P21/02 , A61K49/00 , C12N5/00
CPC分类号: A61K31/337 , A61K39/39558 , A61K2039/505 , A61K2039/507 , C07K16/22 , C07K16/2863 , C07K2317/24 , C07K2317/54 , C07K2317/55 , C07K2317/56 , C07K2317/565 , C07K2317/73 , C07K2317/732 , C07K2317/76 , C07K2317/77 , C07K2317/92 , A61K2300/00
摘要: The invention provides various antibodies that bind to insulin-like growth factor-I receptor (IGF-1R), methods for making such antibodies, compositions and articles incorporating such antibodies, and their uses in treating, for example, cancer or aging. The antibodies include murine, chimeric, and humanized antibodies.
摘要翻译: 本发明提供了结合胰岛素样生长因子-1受体(IGF-1R)的各种抗体,制备此类抗体的方法,掺入此类抗体的组合物和制品及其在治疗例如癌症或衰老中的用途。 抗体包括鼠,嵌合和人源化抗体。