公开(公告)号：US20130195937A1

公开(公告)日：2013-08-01

申请号：US13809617

申请日：2011-07-14

申请人： Yoonhwa Jeong ,  Hyun Jung Lee ,  Do Yeon Lee ,  Yoo Hun Noh ,  Do Hee Kim ,  Ok Hyeon Kim ,  Ji Ae Park ,  Jiwon Lee

发明人： Yoonhwa Jeong ,  Hyun Jung Lee ,  Do Yeon Lee ,  Yoo Hun Noh ,  Do Hee Kim ,  Ok Hyeon Kim ,  Ji Ae Park ,  Jiwon Lee

IPC分类号： A61K33/44 ,  A61K31/166 ,  A61K31/235 ,  A61K9/00 ,  A61K31/192

CPC分类号： A61K33/44 ,  A61B5/04001 ,  A61B5/04002 ,  A61B5/4082 ,  A61B5/4848 ,  A61K9/0092 ,  A61K31/166 ,  A61K31/192 ,  A61K31/235

摘要： A method for preventing or treating a brain nervous disease includes administering to a subject in need thereof a therapeutically effective amount of a carbon nanotube, wherein the nervous disease is a brain disease or a traumatic central nervous system injury. The composition of the present invention enables patients to recover from physical damage to the brain, exhibits superior efficacy for inhibiting the onset of Parkinson's disease and strokes in animal models for Parkinson's disease and strokes, and the cytotoxic effects of beta amyloid in beta amyloid toxicity tests. Therefore, the composition of the present invention can be effectively used in the preparation of medicine for protecting cranial nerves, therapeutic agents for preventing or treating brain disease, or therapeutic agents for treating traumatic injuries to the central nervous system.

摘要翻译： 用于预防或治疗脑神经疾病的方法包括向有需要的受试者施用治疗有效量的碳纳米管，其中所述神经疾病是脑疾病或创伤性中枢神经系统损伤。 本发明的组合物使得患者能够从对脑的物理损伤中恢复，在帕金森病和中风的动物模型中显示出优异的抑制帕金森病发作和中风的功效，以及β淀粉样蛋白在β淀粉样蛋白毒性试验中的细胞毒性作用 。 因此，本发明的组合物可以有效地用于制备用于保护颅神经的药物，用于预防或治疗脑部疾病的治疗剂，或用于治疗对中枢神经系统的创伤性损伤的治疗剂。